{"product_id":"adaptive-design-theory-and-implementation-using-sas-and-r-9781138034235","title":"Adaptive Design Theory and Implementation Using SAS and R","description":"\u003cp\u003e • Author(s): Mark Chang\u003cbr\u003e • Publisher: Taylor \u0026amp; Francis\u003cbr\u003e • Publisher Imprint: CRC Press\u003cbr\u003e • BISAC: Probability \u0026amp; Statistics - General\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cem\u003eGet Up to Speed on Many Types of Adaptive Designs\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003eSince the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials. Incorporating many of these new developments, \u003cstrong\u003eAdaptive Design Theory and Implementation Using SAS and R, Second Edition\u003c\/strong\u003e offers a detailed framework to understand the use of various adaptive design methods in clinical trials. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eNew to the Second Edition\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e \u003cli\u003eTwelve new chapters covering blinded and semi-blinded sample size reestimation design, pick-the-winners design, biomarker-informed adaptive design, Bayesian designs, adaptive multiregional trial design, SAS and R for group sequential design, and much more\u003c\/li\u003e \u003cli\u003eMore analytical methods for K-stage adaptive designs, multiple-endpoint adaptive design, survival modeling, and adaptive treatment switching\u003c\/li\u003e \u003cli\u003eNew material on sequential parallel designs with rerandomization and the skeleton approach in adaptive dose-escalation trials\u003c\/li\u003e \u003cli\u003eTwenty new SAS macros and R functions\u003c\/li\u003e \u003cli\u003eEnhanced end-of-chapter problems that give readers hands-on practice addressing issues encountered in designing real-life adaptive trials\u003c\/li\u003e \u003c\/ul\u003e\u003cp\u003eCovering even more adaptive designs, this book provides biostatisticians, clinical scientists, and regulatory reviewers with up-to-date details on this innovative area in pharmaceutical research and development. Practitioners will be able to improve the efficiency of their trial design, thereby reducing the time and cost of drug development.\u003c\/p\u003e","brand":"Taylor \u0026 Francis","offers":[{"title":"Paperback","offer_id":45237780676759,"sku":"9781138034235","price":5614.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9781138034235.webp?v=1769217605","url":"https:\/\/atlanticbooks.com\/products\/adaptive-design-theory-and-implementation-using-sas-and-r-9781138034235","provider":"Atlantic Books","version":"1.0","type":"link"}