{"product_id":"biopharmaceuticals-9783639136067","title":"Biopharmaceuticals","description":"\u003cp\u003e • Author(s): Nico Wanandy\u003cbr\u003e • Publisher: VDM Verlag\u003cbr\u003e • Publisher Imprint: VDM Verlag\u003cbr\u003e • BISAC: Life Sciences - Biology\u003c\/p\u003e\u003cp\u003eIn the biopharmaceutical industry, essentially, there are three components that play the main role in producing biopharmaceutical products, the host cell, the expression vector and the bioreactor and\/or production environment. To produce the highly valued and desired products, the choice of a suitable host is one of the most important aspects. The host required is not only required to produce the desired product, but also needs to demonstrate robustness in a bioreactor system. Constantly facing challenges in a bioreactor, cells often undergo apoptosis, a well-known limiting factor in biopharmaceutical production, which ultimately leads to low yield of valuable protein(s). We have genetically engineered a CHO-K1 cell line to constitutively express human insulin-like growth factor-1 (IGF-1) and murine polyoma large T-antigen (PyLT-Ag) to generate Super-CHO and CHO-T respectively, two cell lines that can potentially serve different niches in the biopharmaceutical industry.\u003c\/p\u003e","brand":"VDM Verlag","offers":[{"title":"Paperback","offer_id":47610360725655,"sku":"9783639136067","price":7302.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9783639136067.webp?v=1775064443","url":"https:\/\/atlanticbooks.com\/products\/biopharmaceuticals-9783639136067","provider":"Atlantic Books","version":"1.0","type":"link"}