{"product_id":"coenzyme-q-in-aging-9783030456412","title":"Coenzyme Q in Aging","description":"\u003cp\u003e • Author(s): Guillermo López Lluch\u003cbr\u003e • Publisher: Springer\u003cbr\u003e • Publisher Imprint: Springer\u003cbr\u003e • BISAC: Internal Medicine\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFrom the Back Cover\u003c\/b\u003e\u003cbr\u003eThis book offers a comprehensive exploration of research on the essential relationship of the coenzyme Q\u003csub\u003e10\u003c\/sub\u003e and the process of aging in living organisms. CoQ\u003csub\u003e10\u003c\/sub\u003e is an important factor in two main aspects of cell physiology: bioenergetics and antioxidant protection. While primary deficiency of CoQ\u003csub\u003e10\u003c\/sub\u003e is associated with severe and lethal disease, secondary deficiency can be associated with the progression of mitochondrial dysfunction linked to the lessening of biological activities during aging.\u003c\/p\u003e\u003cp\u003eThe book is organized in four sections. The first offers an overview of the function of CoQ\u003csub\u003e10, \u003c\/sub\u003ehighlighting the two main functions of CoQ\u003csub\u003e10\u003c\/sub\u003e in cells: its essential role as electron transport chain member in mitochondria, and the protection of cell membranes against oxidation as one of the main endogenous-synthesized antioxidants. \u003c\/p\u003e \u003cp\u003eThe second section covers research on Coenzyme 10. Topics include studies involving invertebrate models, mammal studies and the influence of CoQ\u003csub\u003e \u003c\/sub\u003eon\u003csub\u003e \u003c\/sub\u003elongevity. Also covered is research involving the role of CoQ in senescence-accelerated mice. \u003c\/p\u003e Section three examines the effects of reduced CoQ in human aging, as evident in mitochondrial dysfunction, metabolic syndrome, neurodegenerative disorders, immunosenescence and fertility and reproduction. \u003cp\u003e\u003c\/p\u003e \u003cp\u003eThe final section, Prolongevity effectors and Coenzyme Q, explores research into slowing or stopping the aging process. Coverage includes strategies including calorie restriction, and modulation of CoQ\u003csub\u003e10\u003c\/sub\u003e levels by induction of synthesis or by supplementation. \u003c\/p\u003e \u003cp\u003e\u003ci\u003eCoenzyme Q in Aging\u003c\/i\u003e benefits a broad readership of researchers, clinicians, educators and students interested in the biochemical and physiological effects of coenzyme Q and the importance of this molecule in aging process. \u003c\/p\u003e","brand":"Springer","offers":[{"title":"Hardcover","offer_id":45279142772887,"sku":"9783030456412","price":11017.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9783030456412.webp?v=1769292794","url":"https:\/\/atlanticbooks.com\/products\/coenzyme-q-in-aging-9783030456412","provider":"Atlantic Books","version":"1.0","type":"link"}