{"product_id":"dna-modifications-methods-and-protocols-9781071608784","title":"DNA Modifications: Methods and Protocols","description":"\u003cp\u003e • Author(s): Alexey Ruzov\u003cbr\u003e • Publisher: Springer\u003cbr\u003e • Publisher Imprint: Humana\u003cbr\u003e • BISAC: Life Sciences - Biology\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFrom the Back Cover\u003c\/b\u003e\u003cbr\u003eThis book provides an overview of methods and experimental protocols that are currently used to analyze the presence and abundance of non-canonical DNA nucleotides in different biological systems. Focusing particularly on the newly discovered and less studied DNA modifications that are enzymatically produced and are likely to play specific roles in various biological processes, the volume explores chromatography- and mass spectrometry-based techniques for the detection and quantification of DNA modifications, antibody-based approaches to study their spatial distribution in different cells and tissues, and methods to analyze their genomic distribution with the help of bioinformatics tools that interrogate the corresponding datasets. Written for the highly successful \u003ci\u003eMethods in Molecular Biology\u003c\/i\u003e series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. \u003cbr\u003eAuthoritative and comprehensive, \u003ci\u003eDNA Modifications: Methods and Protocols\u003c\/i\u003e serves as an ideal guide to research scientists and PhD students in this rapidly developing discipline, and, thus, will ultimately contribute to deciphering the roles of non-canonical DNA nucleotides in different biological systems.\u003c\/p\u003e","brand":"Springer","offers":[{"title":"Paperback","offer_id":45279463145623,"sku":"9781071608784","price":12007.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9781071608784.webp?v=1769293645","url":"https:\/\/atlanticbooks.com\/products\/dna-modifications-methods-and-protocols-9781071608784","provider":"Atlantic Books","version":"1.0","type":"link"}