{"product_id":"drug-metabolism-and-pharmacokinetics-frontiers-strategies-and-applications-9781394300129","title":"Drug Metabolism and Pharmacokinetics: Frontiers, Strategies, and Applications","description":"\u003cp\u003e • Author(s): Liang Shen\u003cbr\u003e • Publisher: Wiley\u003cbr\u003e • Publisher Imprint: Wiley\u003cbr\u003e • BISAC: Pharmacology\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePractical, state-of-the-art pharmacokinetic research methods, ideas, advancements, applications, and strategies\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eDrawing on a wealth of extensive practical experience and theoretical research, \u003ci\u003eDrug Metabolism and Pharmacokinetics\u003c\/i\u003e encapsulates the most recent advancements and illustrative applications in the field. Sixty-eight relatively independent yet interconnected articles are included, each offering a unique perspective and providing in-depth interpretation. Readers can either read systematically or select specific topics of interest from the table of contents. \u003c\/p\u003e\u003cp\u003eBasic concepts, frontier advancements, DMPK research strategies, and technical methods are covered for novel drug modalities and therapeutics in different disease areas. The book encompasses a wide range of application and validation cases for DMPK research, including studies in \u003ci\u003ein vitro\u003c\/i\u003e ADME, \u003ci\u003ein vivo\u003c\/i\u003e pharmacokinetics, metabolite profiling and identification, radiolabeled ADME, and bioanalysis. Case studies showing the application of topics covered are included throughout, along with valuable insights into problem-solving and critical thinking. \u003c\/p\u003e\u003cp\u003eWritten by a team of scientists specializing in DMPK research from the DMPK Department of WuXi AppTec, \u003ci\u003eDrug Metabolism and Pharmacokinetics\u003c\/i\u003e discusses sample topics including:  *ADME characteristics, metabolite identification, and bioanalytical strategies for  oligonucleotide drugs *Strategy and challenges in the determination of drug-to-antibody ratio (DAR) values and antibody-drug conjugates (ADCs) *Breaking barriers in CNS drug development with intrathecal and intracerebroventricular administration *Application and detection techniques of biomarkers in drug development *Flux dialysis methods for assessing plasma protein binding of high protein-binding drugs  \u003c\/p\u003e\u003cp\u003eDrug Metabolism and Pharmacokinetics is an essential forward-thinking reference on the subject for pharmacy students, pharmaceutical industry researchers, and DMPK scientists, especially those exploring novel drug modalities.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Hardcover","offer_id":45202302271639,"sku":"9781394300129","price":17999.0,"currency_code":"INR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9781394300129.webp?v=1767668129","url":"https:\/\/atlanticbooks.com\/products\/drug-metabolism-and-pharmacokinetics-frontiers-strategies-and-applications-9781394300129","provider":"Atlantic Books","version":"1.0","type":"link"}