{"product_id":"future-challenges-for-the-diagnosis-and-management-of-affective-disorders-from-preclinical-evidence-to-clinical-trials-9783725860715","title":"Future Challenges for the Diagnosis and Management of Affective Disorders: From Preclinical Evidence to Clinical Trials","description":"\u003cp\u003e • Author(s): Antonio Ventriglio | Mario Luciano | Andrea Fiorillo\u003cbr\u003e • Publisher: Mdpi AG\u003cbr\u003e • Publisher Imprint: Mdpi AG\u003cbr\u003e • BISAC: Pharmacology\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis Special Issue presents preclinical and clinical research aimed at reframing the diagnosis and treatment of affective disorders beyond classical neurobiological models. It includes a meta-analysis comparing single- versus two-dose psilocybin administration in major depressive disorder, clarifying its efficacy and dose-dependency. Another study uses network analysis of exposome scores to link environmental exposure with multidimensional psychopathology in non-clinical samples, while the effects of light pollution on affective health highlight chronobiological disruption in mood disorder etiology.\u003c\/p\u003e\u003cp\u003eDiagnostic and clinical dimensions are explored through research on polarity at bipolar disorder onset, mapping temperamental correlates and long-term trajectories. Biomarker studies report elevated mature brain-derived neurotrophic factor (BDNF) levels associated with suicidal ideation in major depressive disorder and evaluate BDNF's validity in bipolar disorder. Perinatal and familial aspects are explored in a structural equation modeling study showing how attachment-related coping mediates postpartum depressive symptoms and which develops a protocol for a randomized clinical trial for a psychoeducational family intervention in major depressive disorder. Together, these contributions outline a multidimensional landscape integrating environmental, temperamental, biological, and psychosocial determinants.\u003c\/p\u003e","brand":"Mdpi AG","offers":[{"title":"Hardcover","offer_id":47594781835415,"sku":"9783725860715","price":6000.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9783725860715.webp?v=1774987136","url":"https:\/\/atlanticbooks.com\/products\/future-challenges-for-the-diagnosis-and-management-of-affective-disorders-from-preclinical-evidence-to-clinical-trials-9783725860715","provider":"Atlantic Books","version":"1.0","type":"link"}