{"product_id":"g-quadruplex-dna-methods-and-protocols-9781493956395","title":"G-Quadruplex DNA: Methods and Protocols","description":"\u003cp\u003e • Author(s): Peter Baumann\u003cbr\u003e • Publisher: Springer\u003cbr\u003e • Publisher Imprint: Humana\u003cbr\u003e • BISAC: Life Sciences - Genetics \u0026amp; Genomics\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFrom the Back Cover\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eRecent work has revealed that stabilizing G-quadruplexes in telomeric DNA inhibits telomerase activity, providing impetus for the development of G-quartet-interacting drugs, while G-quartet-containing oligonucleotides have been recognized as a potent class of aptamers effective against STAT3 and other transcription factors implicated in oncogenesis, proving these guanine-quartets to be a vital and rich area for future study. In \u003cem\u003eG-Quadruplex DNA: Methods and Protocols\u003c\/em\u003e, experts in the field present a collection of detailed techniques for studying G-quartet formation, dynamics, and molecular recognition. Written in the highly successful \u003cem\u003eMethods in Molecular Biology\u003c\/em\u003e(TM) series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e \u003cp\u003e\u003c\/p\u003e \u003cp\u003eAuthoritative and cutting-edge, \u003cem\u003eG-Quadruplex DNA: Methods and Protocols\u003c\/em\u003e promises to be a useful resource for those familiar with G-quartets as well as an easy entry point for those researchers from diverse fields who are just developing an interest in the exciting implications of G-quadruplex DNA.\u003c\/p\u003e","brand":"Springer","offers":[{"title":"Paperback","offer_id":45274871562391,"sku":"9781493956395","price":8005.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9781493956395.webp?v=1769281190","url":"https:\/\/atlanticbooks.com\/products\/g-quadruplex-dna-methods-and-protocols-9781493956395","provider":"Atlantic Books","version":"1.0","type":"link"}