{"product_id":"icrp-publication-152-radiation-detriment-calculation-methodology-9781529619003","title":"ICRP Publication 152: Radiation Detriment Calculation Methodology","description":"\u003cp\u003e • Author(s): Icrp\u003cbr\u003e • Publisher: Sage Publications UK\u003cbr\u003e • Publisher Imprint: Sage Publications UK\u003cbr\u003e • BISAC: Radiology, Radiotherapy \u0026amp; Nuclear Medicine\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eRadiation detriment is a concept developed by the International Commission\u003c\/p\u003e\u003cp\u003eon Radiological Protection to quantify the burden of stochastic effects from lowdose\u003c\/p\u003e\u003cp\u003eand\/or low-dose-rate exposures to the human population. It is determined from\u003c\/p\u003e\u003cp\u003ethe lifetime risks of cancer for a set of organs and tissues and the risk of heritable\u003c\/p\u003e\u003cp\u003eeffects, taking into account the severity of the consequences. This publication provides\u003c\/p\u003e\u003cp\u003ea historical review of detriment calculation methodology since ICRP\u003c\/p\u003e\u003cp\u003ePublication 26, with details of the procedure developed in ICRP Publication 103, \u003c\/p\u003e\u003cp\u003ewhich clarifies data sources, risk models, computational methods, and rationale for\u003c\/p\u003e\u003cp\u003ethe choice of parameter values. A selected sensitivity analysis was conducted to\u003c\/p\u003e\u003cp\u003eidentify the parameters and calculation conditions that can be major sources of\u003c\/p\u003e\u003cp\u003evariation and uncertainty in the calculation of radiation detriment. It has demonstrated\u003c\/p\u003e\u003cp\u003ethat sex, age at exposure, dose and dose-rate effectiveness factor, dose\u003c\/p\u003e\u003cp\u003eassumption in the calculation of lifetime risk, and lethality fraction have a substantial\u003c\/p\u003e\u003cp\u003eimpact on radiation detriment values. Although the current scheme of radiation\u003c\/p\u003e\u003cp\u003edetriment calculation is well established, it needs to evolve to better reflect changes in\u003c\/p\u003e\u003cp\u003epopulation health statistics and progress in scientific understanding of radiation\u003c\/p\u003e\u003cp\u003ehealth effects. In this regard, some key parameters require updating, such as the\u003c\/p\u003e\u003cp\u003ereference population data and cancer severity. There is also room for improvement\u003c\/p\u003e\u003cp\u003ein cancer risk models based on the accumulation of recent epidemiological findings.\u003c\/p\u003e\u003cp\u003eFinally, the importance of improving the comprehensibility of the detriment concept\u003c\/p\u003e\u003cp\u003eand the transparency of its calculation process is emphasised.\u003c\/p\u003e","brand":"Atlantic Books","offers":[{"title":"Paperback","offer_id":46441142845591,"sku":"9781529619003","price":50591.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9781529619003.webp?v=1769117711","url":"https:\/\/atlanticbooks.com\/products\/icrp-publication-152-radiation-detriment-calculation-methodology-9781529619003","provider":"Atlantic Books","version":"1.0","type":"link"}