{"product_id":"life-and-science-lowered-levels-of-sperm-9780190221225","title":"LIFE AND SCIENCE lowered levels of sperm","description":"\u003cp\u003e • Author(s): Elio E\u003cbr\u003e • Publisher: Elio Endless Publishers\u003cbr\u003e • Publisher Imprint: Elio Endless Publishers\u003cbr\u003e • BISAC: Americas (North Central South West Indies)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eIt's a gem that our awesome publishing company has brought to\u003c\/p\u003e\u003cp\u003elife. Now, as part of my job, I get to dive into countless books, and I must\u003c\/p\u003e\u003cp\u003esay, this one is an absolute delight. No need for any unnecessary delay, let\u003c\/p\u003e\u003cp\u003eme give you a sneak peek into what makes it so worthwhile. Are you ready?\u003c\/p\u003e\u003cp\u003eLet's jump right in with the introduction Age-related endocrine disruption\u003c\/p\u003e\u003cp\u003ehas been linked to cognitive decline and an increased risk of\u003c\/p\u003e\u003cp\u003eneurodegenerative illnesses, as evidenced by a growing body of research.\u003c\/p\u003e\u003cp\u003eAlthough oestrogens have long been thought to safeguard brain function, it\u003c\/p\u003e\u003cp\u003ewas only recently discovered that androgens and luteinizing hormone can\u003c\/p\u003e\u003cp\u003eaffect cognitive processes by altering how we learn and remember things.\u003c\/p\u003e\u003cp\u003eImproving treatment for cognitive impairment linked to the hypothalamicpituitary-\u003c\/p\u003e\u003cp\u003egonadal axis requires a deeper understanding of the underlying\u003c\/p\u003e\u003cp\u003emechanisms. In this article, we highlight the role of reproductive hormones\u003c\/p\u003e\u003cp\u003ein preserving brain health and amplifying signalling cascades that lead to\u003c\/p\u003e\u003cp\u003ePreface\u003c\/p\u003e\u003cp\u003emental decline. We discuss the endocrine changes that occur with age, their\u003c\/p\u003e\u003cp\u003erole in the onset of Alzheimer's disease, and the therapeutic potential of\u003c\/p\u003e\u003cp\u003eendocrine manipulation in preventing cognitive decline in the\u003c\/p\u003e\u003cp\u003eelderly.Menopause, oophorectomy, oestrogen, testosterone, memory loss, \u003c\/p\u003e\u003cp\u003eAlzheimer's disease, and luteinizing hormone are all terms of interest.The\u003c\/p\u003e\u003cp\u003erisk of age-related neurodegenerative disorders like Alzheimer's disease\u003c\/p\u003e\u003cp\u003e(AD) is increasingly important to think about as the baby boomer\u003c\/p\u003e\u003cp\u003egeneration ages and life expectancy increases thanks to medical\u003c\/p\u003e\u003cp\u003eadvancements. By 2050, it's expected that over 13 million people would\u003c\/p\u003e\u003cp\u003ehave been diagnosed with AD. Dementia is one of the most expensive\u003c\/p\u003e\u003cp\u003ediseases, with annual costs of care for people with Alzheimer's disease and\u003c\/p\u003e\u003cp\u003eother forms of dementia estimated at over $180 billion in the United States\u003c\/p\u003e\u003cp\u003ealone. As the prevalence of neurodegenerative diseases increases, so too\u003c\/p\u003e\u003cp\u003ewill the emotional, mental, and financial strains placed on those who\u003c\/p\u003e\u003cp\u003eprovide care for those who have been diagnosed.Amyloid- senile plaques, \u003c\/p\u003e\u003cp\u003eneurofibrillary tangles made of aggregated tau, and hippocampal cell loss\u003c\/p\u003e\u003cp\u003eare the classic neuropathologies of Alzheimer's disease. Clinically, AD is\u003c\/p\u003e\u003cp\u003edistinguished by memory and attention difficulties, which deteriorate into\u003c\/p\u003e\u003cp\u003eproblems with reasoning, communication, and direction as the disease\u003c\/p\u003e\u003cp\u003eadvances. Although oxidative stress, inflammation, and neuronal\u003c\/p\u003e\u003cp\u003edysfunction have all been implicated in the development of Alzheimer's\u003c\/p\u003e\u003cp\u003edisease, conclusive data explaining disease pathogenesis is lacking; as a\u003c\/p\u003e\u003cp\u003eresult, we and others have been forced to look beyond these basic\u003c\/p\u003e\u003cp\u003epathologies in search of other molecular cues driving AD pathogenesis.The\u003c\/p\u003e\u003cp\u003eeffect of gonadal hormones on cognition in the elderly has been the subject\u003c\/p\u003e\u003cp\u003eof substantial research. Hormones are known to impact CNS function and\u003c\/p\u003e\u003cp\u003estability.\u003c\/p\u003e","brand":"Elio Endless Publishers","offers":[{"title":"Misc","offer_id":45115378991255,"sku":"9780190221225","price":2064.0,"currency_code":"INR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9780190221225.webp?v=1768546613","url":"https:\/\/atlanticbooks.com\/products\/life-and-science-lowered-levels-of-sperm-9780190221225","provider":"Atlantic Books","version":"1.0","type":"link"}