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Peptides bioactifs du lait by Leblanc-J

Peptides bioactifs du lait

by Leblanc-J
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Book cover type: Paperback
  • ISBN13: 9786131544323
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Omniscriptum
  • Publisher Imprint: Omniscriptum
  • Publication Date:
  • Pages: 72
  • Original Price: GBP 25.0
  • Language: French
  • Edition: N/A
  • Item Weight: 118 grams
  • BISAC Subject(s): Life Sciences / Biochemistry

Le lait fermenté par Lactobacillus helveticus R389, une bactérie lactique reconnue pour son haut potentiel protéolytique, a été fractionné par HPLC puis les paramètres de la réponse immune de chacune des fractions ont été étudiés in vivo. Cette étude a permis d'identifier des fractions peptidiques relarguées après fermentation du lait capables d'augmenter la quantité de cellules B productrices d'IgA au niveau intestinal et de régresser la croissance des fibrosarcomes. L'augmentation de ces cellules B est importante pour l'hôte, car ces anticorps constituent une barrière contre la néoplasie ainsi que contre plusieurs agents infectieux. Comme il existe un cycle commun aux anticorps IgAs au niveau du muqueuses, une stimulation au niveau d'un site, par exemple dans les intestins pourrait induire une protection générale au niveau des autres sites des muqueuses (i.e. poumons, système uro-génital). La régression de la croissance des fibrosarcomes, une tumeur épithéliale immunodépendante, démontre que plusieurs mécanismes immunitaires sont affectés par l'ingestion de fractions peptidiques. Ce travail ouvre la voie à des études innovatrices dans le domaine des peptides bioactifs.

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