{"product_id":"phenotypes-and-genotypes-the-search-for-influential-genes-9781447153092","title":"Phenotypes and Genotypes: The Search for Influential Genes","description":"\u003cp\u003e • Author(s): Florian Frommlet\u003cbr\u003e • Publisher: Springer\u003cbr\u003e • Publisher Imprint: Springer\u003cbr\u003e • BISAC: Life Sciences - Genetics \u0026amp; Genomics\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFrom the Back Cover\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eThis timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eTopics and features: \u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e \u003cp\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003ePresents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical)\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eReviews the latest advances in the field, highlighting the advantages and shortcomings of the currently most commonly used methods\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eIllustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eDiscusses open challenges that remain to be solved in the future\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eIncludes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003eThis important work is essential reading for researchers and graduate students wishing to enter the field of statistical genetics and\/or interested in statistical issues related to the analysis of high-dimensional data. No prior background knowledge of genetics is required, although some basic mathematical and computer science skills are assumed.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDr. Florian Frommlet\u003c\/b\u003e is a researcher in the Center for Medical Statistics, Informatics, and Intelligent Systems at the Medical University of Vienna, Austria. \u003cb\u003eDr. Malgorzata Bogdan\u003c\/b\u003e is an Associate Professor in the Institute of Mathematics at Wroclaw University, Poland. \u003cb\u003eDr. David Ramsey\u003c\/b\u003e is a Senior Lecturer in the Department of Operations Research at Wroclaw University of Technology, Poland.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e","brand":"Springer","offers":[{"title":"Hardcover","offer_id":45277054206103,"sku":"9781447153092","price":7345.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9781447153092.webp?v=1769287362","url":"https:\/\/atlanticbooks.com\/products\/phenotypes-and-genotypes-the-search-for-influential-genes-9781447153092","provider":"Atlantic Books","version":"1.0","type":"link"}