{"product_id":"progress-in-medicinal-chemistry-9780444509598","title":"Progress in Medicinal Chemistry","description":"\u003cp\u003e • Author(s): F. D. King\u003cbr\u003e • Publisher: Elsevier Science\u003cbr\u003e • Publisher Imprint: Elsevier Science\u003cbr\u003e • BISAC: Pharmacology\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis volume covers contemporary advances in five important areas of pharmacology and medicinal chemistry including: a comprehensive account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of anti-inflammatory and antiapoptotic agents of potential value in rheumatoid arthritis, and other peripheral and central indications; adoc umented survey of semi-synthetic and totally synthetic antibiotics and anti HIV agents and their sites of interaction; inhibitors of the intracellular enzyme acyl-CoA: cholesterol O-acyltransferase (ACAT) developed for the treatment of hypercholesterolemia; and recent progress in growth hormone secretagogues, with the focus on strategies to improve oral bioavailability and duration of action. Inhibition of the proteolytic enzyme, hepatitis C protease N-3(NS3), required for viral replication, is one of the most attractive targets for HCV infections. Progress and prospects in the design of peptide and non-peptide inhibitors are described here. design and clinical potential of new drug molecules; valuable summaries of structure-activity relationships in topical areas of medicinal chemistry; and extensive references to the biology, medicinal chemistry and clinical aspects of each topic.\u003c\/p\u003e","brand":"Elsevier Science","offers":[{"title":"Hardcover","offer_id":45310334697623,"sku":"9780444509598","price":12002.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9780444509598.webp?v=1769287639","url":"https:\/\/atlanticbooks.com\/products\/progress-in-medicinal-chemistry-9780444509598","provider":"Atlantic Books","version":"1.0","type":"link"}