{"product_id":"progress-in-medicinal-chemistry-9780444511430","title":"Progress in Medicinal Chemistry","description":"\u003cp\u003e • Author(s): F. D. King\u003cbr\u003e • Publisher: Elsevier\u003cbr\u003e • Publisher Imprint: Elsevier\u003cbr\u003e • BISAC: Pharmacology\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis volume includes information on recent advances in five important areas: an account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of anti-inflammatory and antiapoptotic agents of potential value in rheumatoid arthritis; and a survey of semi-synthetic and totally synthetic antibiotics and anti-HIV agents and their sites of interaction; the development of inhibitors of the intracellular enzyme acyl-CoA: cholesterol O-acyltransferase (ACAT) for the treatment of hypercholesterolemia; a description of recent progress in growth hormone secretagogues, with the focus on strategies to improve oral bioavailability and duration of action; and information on inhibition of the proteolytic enzyme, hepatitis C protease N-3(NS3), (required for vital replication) as one of the most attractive targets for HCV infections.\u003c\/p\u003e","brand":"Elsevier","offers":[{"title":"Hardcover","offer_id":45310334861463,"sku":"9780444511430","price":12172.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9780444511430.webp?v=1769287638","url":"https:\/\/atlanticbooks.com\/products\/progress-in-medicinal-chemistry-9780444511430","provider":"Atlantic Books","version":"1.0","type":"link"}