{"product_id":"ras-family-gtpases-9781402043284","title":"Ras Family Gtpases","description":"\u003cp\u003e • Author(s): Channing Der\u003cbr\u003e • Publisher: Springer\u003cbr\u003e • Publisher Imprint: Springer\u003cbr\u003e • BISAC: Life Sciences - Biology\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFrom the Back Cover\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eSince 1982, Ras proteins have been the subject of intense research investigation by the\u003c\/p\u003e \u003cp\u003ebiomedical research community. The wide interest in Ras has been stimulated for\u003c\/p\u003e \u003cp\u003ethree key reasons.\u003c\/p\u003e \u003cp\u003eFirst, their frequent mutational activation in human cancers establishes Ras proteins\u003c\/p\u003e \u003cp\u003eas important mediators of oncogenesis and targets for anti-cancer drug discovery.\u003c\/p\u003e \u003cp\u003eSecond, Ras proteins act as signalling nodes activated by diverse extracellular\u003c\/p\u003e \u003cp\u003estimuli, and activated Ras in turn regulates a diversity of cytoplasmic signalling\u003c\/p\u003e \u003cp\u003enetworks.\u003c\/p\u003e \u003cp\u003eThird, Ras proteins are founding members of a large superfamily of Ras-related small\u003c\/p\u003e \u003cp\u003eGTPases. Over 150 Ras-related small GTPases are found in the human genome, with\u003c\/p\u003e \u003cp\u003eorthologs found in all vertebrate species and invertebrates.\u003c\/p\u003e \u003cp\u003eThis book features chapters by leading investigators in the field that highlight the\u003c\/p\u003e \u003cp\u003ecurrent state-of-the art in Ras biochemistry, structure and biology.\u003c\/p\u003e \u003cp\u003eThis book is an excellent reference for students in the biomedical sciences and for\u003c\/p\u003e \u003cp\u003einvestigators in the field.\u003c\/p\u003e","brand":"Springer","offers":[{"title":"Hardcover","offer_id":45274919764119,"sku":"9781402043284","price":15987.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9781402043284.webp?v=1769281330","url":"https:\/\/atlanticbooks.com\/products\/ras-family-gtpases-9781402043284","provider":"Atlantic Books","version":"1.0","type":"link"}