{"product_id":"simvastatin-solid-dispersion-prepared-by-microwave-fusion-technique-9783846504055","title":"Simvastatin Solid Dispersion Prepared by Microwave Fusion Technique","description":"\u003cp\u003e • Author(s): Chaudhary Haresh | Patel B. N. | Patel D. M.\u003cbr\u003e • Publisher: LAP Lambert Academic Publishing\u003cbr\u003e • Publisher Imprint: LAP Lambert Academic Publishing\u003cbr\u003e • BISAC: Pharmacology\u003c\/p\u003e\u003cp\u003eSimvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg\/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose of this study was to apply the attractive technique of the microwaves fusion for the preparation of solvent-Simvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg\/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose of this study was to apply the attractive technique of the microwaves fusion for the preparation of solvent-free solid dispersions and to enhance the solubility and dissolution rate of simvastatin by a solid dispersion.\u003c\/p\u003e","brand":"Atlantic Books","offers":[{"title":"Paperback","offer_id":46500889493655,"sku":"9783846504055","price":5063.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9783846504055.webp?v=1769195789","url":"https:\/\/atlanticbooks.com\/products\/simvastatin-solid-dispersion-prepared-by-microwave-fusion-technique-9783846504055","provider":"Atlantic Books","version":"1.0","type":"link"}