{"product_id":"structural-biology-in-drug-discovery-methods-techniques-and-practices-9781118681015","title":"Structural Biology in Drug Discovery: Methods, Techniques, and Practices","description":"\u003cp\u003e • Author(s): Jean-Paul Renaud\u003cbr\u003e • Publisher: Wiley\u003cbr\u003e • Publisher Imprint: Wiley\u003cbr\u003e • BISAC: Pharmacology\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eWith the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, \u003ci\u003eStructural Biology in Drug Discovery: Methods, Techniques, and Practices\u003c\/i\u003e describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field.\u003cbr\u003e\u003cbr\u003eThe combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that:\u003c\/p\u003e  *Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology *Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design *Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures *Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins","brand":"Wiley","offers":[{"title":"Hardcover","offer_id":45202306826391,"sku":"9781118681015","price":19773.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9781118681015.webp?v=1769208173","url":"https:\/\/atlanticbooks.com\/products\/structural-biology-in-drug-discovery-methods-techniques-and-practices-9781118681015","provider":"Atlantic Books","version":"1.0","type":"link"}