{"product_id":"systems-chemical-biology-methods-and-protocols-9781493988907","title":"Systems Chemical Biology: Methods and Protocols","description":"\u003cp\u003e • Author(s): Slava Ziegler\u003cbr\u003e • Publisher: Springer\u003cbr\u003e • Publisher Imprint: Humana\u003cbr\u003e • BISAC: Life Sciences - Anatomy \u0026amp; Physiology\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFrom the Back Cover\u003c\/b\u003e\u003cbr\u003eThis volume explores the latest available wet-lab techniques and computational methods to study in-cell small-molecule behavior and interactions with their targets. The chapters in this book discuss topics such as disease-relevant models for chemical biology studies, target engagement using cellular thermal shift assay or bioluminescence resonance energy transfer; visualization of bio-active small molecules Raman microscopy; (phospho-)proteomics and transcriptomics for mode-of-action studies, CRISPR\/Cas9-based chemogenomic profiling in mammalian cells; predicting drug interactions using computational approaches; comparison of compound-induced profiles using high-content imaging or cancer cell line panels and web-based tools for polypharmacology prediction. Written in the highly successful \u003ci\u003eMethods in Molecular Biology\u003c\/i\u003e series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003eCutting-edge and thorough, \u003ci\u003eSystems Chemical Biology: Methods and Protocols \u003c\/i\u003eis a valuable resource for novice or expert scientists and researchers trying to initiate or continue their chemical biology studies at a systems level.\u003cbr\u003e","brand":"Springer","offers":[{"title":"Hardcover","offer_id":45280063422615,"sku":"9781493988907","price":11017.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0666\/3471\/1191\/files\/9781493988907.webp?v=1769295273","url":"https:\/\/atlanticbooks.com\/products\/systems-chemical-biology-methods-and-protocols-9781493988907","provider":"Atlantic Books","version":"1.0","type":"link"}