Practical Medicinal Chemistry with Macrocycles: Design, Synthesis, and Case Studies (Hardbound - 2017)

Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts.

• Provides needed background to build a program in macrocycle drug discovery -design criteria, macrocycle profiles, applications, and limitations
• Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts
• Covers design criteria, typical profile of current macrocycles, applications, and limitations