• ISBN13: 9780824702649
• Binding: Hardcover
• Subject: Medical, Nursing and Health Sciences
• Publisher: T&F
• Publisher Imprint: Mar Dekker
• Publication Date: April 6, 2001
• Pages: 639
• Original Price: 118.0 GBP
• Language: English
• Edition: N/A
• Item Weight: 1500 grams

About the Book Compiling the latest developments in anticancer therapies based on the connection between tumor and capillary growth, Tumor Angiogenesis and Microcirculation presents a comprehensive overview of diverse aspects of angiogenesis-related cancer research. <br>Highlights the role angiogenesis and its inhibitors play in the growth, metastasis, and dormancy of tumors <br>Facilitating the progress of clinical practice with insights from methodological and scientific results, Tumor Angiogenesis and Microcirculation <br><li>summarizes biological principles of angiogenesis and microcirculation, from endothelial cells and pericytes, and extracellular matrix regulation to matrix metalloproteinases (MMPs) and plasmin and plasmin inhibitors<br></li><li>examines proangiogenic factors such as vascular endothelial (VEGF) and basic fibroblast (bFGF) growth factors, tie receptors, and cytokines <br></li><li>outlines methods for discovering angiogenesis stimulators and inhibitor peptides, particularly the clinical development of thrombospondin, angiostatin, endostatin, and MMP inhibitors <br></li><li>reveals the link between oncogenes and neoplastic angiogenesis and its regulation by the organ microenvironment <br></li><li>investigates tumor vascularity in relation to tumor growth and the spread of cancer<br></li><li>details promising future applications, including perspectives in vascular cancer therapy<br></li><li>and more <br>Combining the resources of 60 recognized experts and nearly 3000 pertinent literature references, drawings, photographs, and x-rays, Tumor Angiogenesis and Microcirculation profits oncologists, pathologists, hematologists, and radiation and hemato-oncologists; surgeons and internists; cardiologists; immunologists; cell, molecular, and developmental biologists; rheumatologists; ophthalmologists; dermatologists; and medical school students in these disciplines.</li>