Gene Discovery For Disease Models
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From the Back Cover
New concepts in gene discovery in the post-genome era
The completion of human and other genome sequencing, along with other new technologies, such as mutation analysis and microarray, has dramatically accelerated progress in the positional cloning of genes from mutated models. Gene Discovery for Disease Models provides readers with a comprehensive understanding of the new concepts and protocols implemented in gene discovery in the present post-genome era.
Backed by sound scientific findings, this informative guide not only provides a systematic introduction to the available resources and technologies for gene discovery but, most importantly, teaches readers how to use all the available tools and data to find new mutated genes. Its comprehensive coverage:
Provides a detailed description of positional cloning and genomic cloning
Identifies genes of human disease and animal models
Suggests new paradigms for mutation discovery in the post-genome era
Describes new concepts in gene discovery in the post-genome era and the use of streamlined protocols to identify genes of interest
Gene Discovery for Disease Models helps researchers to not only understand the current concepts and technologies, but also learn how to take advantage of these new resources and technologies in the future and adapt to emerging new discoveries in the genetic sciences. This book can be used as a handbook for gene cloning and discovery, as well as a reference book for teachers and students in the fields of genetics and biology.
Weikuan Gu received his PhD from Cornell University in 1994 and joined the University of Tennessee Health Science Center as an assistant professor in 2002. Dr. Gu's lab has developed an integrated strategy for the positional cloning of genes, a strategy which has been successfully applied to clone several genes from spontaneous mouse mutations.
Yongjun Wang received his MD from Hebei Medical College in 1982 and his MBA from Peking University in 2004. Dr. Wang joined Beijing Tiantan Hospital in 2000 and now serves as the vice president of the hospital.
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