Dynamic Stereochemistry Of Chiral Compounds: Principles and Applications
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From the Back Cover
In this book the reader is presented with a comprehensive overview of fundamental concepts of asymmetric synthesis along with in-depth discussion of strategies for the synthesis and stereoselective interconversion of compounds exhibiting central axial and planar chirality, numerous racemization and diastereomerization reactions. Details of analytical methods are provided and discussed as well as topics relating to the design of fascinating topologically chiral assemblies and molecular technomimetic devices in the context of dynamic stereochemistry. Strategies and recent developments that address important synthetic challenges are also presented. This exceptional book includes: - more than 550 figures, schemes and tables illustrating mechanisms of numerous asymmetric reactions and stereomutations of chiral compounds -Technical drawings illustrating the conceptual linkage between macroscopic devices such as turnstiles, ratchets, brakes, bevel gears or knots and molecular analogs. - More than 3000 references to encourage further reading and facilitate additional literature research - A comprehensive glossary with stereochemical definitions and terms which facilitate understanding and reinforce learning This book will be of particular interest to undergraduates, graduates and professionals working and reseraching in the fields of organic synthetic chemistry and analytical chemistry.
Wolf, Christian: - Professor Christian Wolf graduated from the University of Hamburg, Germany in 1993 where he received his Ph.D. in 1995 under the auspices of Professor Wilfried A. König. After working as a postdoctoral Feodor-Lynen Fellow with Professor William H. Pirkle at the University of Illinois in Urbana, Illinois he took an R&D position at SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania in 1997. In 2000, he accepted a position as Assistant Professor in the Chemistry Department at Georgetown University in Washington, DC where he was promoted to Associate Professor with tenure in 2006. He has been a visiting scholar at the University of Reading, England in 1991 and at the University of Aix-Marseille, France in 1995. Professor Wolf's research interests comprise stereodynamics of chiral compounds, asymmetric synthesis, stereoselective sensing, chiral recognition, transition metal-catalyzed cross-coupling reactions, development of antimalarial drugs, and chiral chromatography.
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