Name: Therapeutic Oligonucleotides
Brand: Royal Society of Che
SKU: 9780854041169
Price: 4443.0 INR
Availability: InStock

Therapeutic Oligonucleotides

by C. A. Stein , Others

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ISBN13: 9780854041169
Binding: Hardcover
Subject: Chemistry
Publisher: Royal Society of Che
Publisher Imprint: RSC
Publication Date: January 1, 2008
Pages: 343
Original Price: GBP 144.99
Language: English
Edition: N/A
Item Weight: 699 grams
BISAC Subject(s): Life Sciences / Biochemistry, Pharmacology, and Chemistry / Organic

About The Book

From the Back Cover
Oligonucleotides are a promising new class of biomacromolecules for various therapeutic purposes to treat cancer, viral infections and inflammatory diseases. Antisense oligonucleotides against the cytomegalovirus and an aptamer to treat an ocular disease have already been approved by the regulatory authorities. A number of additional oligonucleotides including small interfering RNAs are currently in various phases of clinical development. Therapeutic Oligonucleotides provides a comprehensive overview of the development of oligonucleotides for therapeutic applications, touching on a number of different strategies with a special focus on the latest progress in the field of RNA interference. The book covers a wide range of topics: antisense oligonucleotides, small interfering and short hairpin RNAs, decoy and immune stimulatory oligonucleotides and aptamers as well as delivery of oligonucleotides. Written by experts in the field, both academic and industrial, Therapeutic Oligonucleotides provides a compelling overall update on current status of research and clinical development and will also serve as a valid resource for researchers and students as well as academics, consultants and scientists.

About The Author

Jens Kurreck is professor for nucleic acids technologies at the University of Stuttgart (Germany). He received his PhD at the Technical University Berlin in 1998 and was a postdoc at the Arizona State University in Tempe, USA. From 1999 to 2007 he was assistant professor ('Habilitand') at the Free University Berlin. Furthermore, he holds a master's degree in philosophy. His group has been working in the field of gene silencing for many years with a focus on pain research and heart muscle infections. In 2005, Jens Kurreck received the award for the best teaching at the biochemistry department as well as the Young Scientist Lectureship Award of the European Society for Neurochemistry (ESN).

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