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Biomarkers in Breast Cancer

by Giampietro Gasparini , Daniel F. Hayes
Save 17% Save 17%
Current price ₹22,526.00
Original price ₹27,032.00
Original price ₹27,032.00
Original price ₹27,032.00
(-17%)
₹22,526.00
Current price ₹22,526.00

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Book cover type: Hardcover
  • ISBN13: 9781588292278
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: Humana
  • Publisher Imprint: Humana
  • Publication Date:
  • Pages: 342
  • Original Price: USD 219.99
  • Language: English
  • Edition: 2006
  • Item Weight: 862 grams
  • BISAC Subject(s): Diseases & Conditions / Cancer

Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.

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