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Chemokine Receptors In Cancer

by Amy M. Fulton
Save 17% Save 17%
Current price ₹16,204.00
Original price ₹19,445.00
Original price ₹19,445.00
Original price ₹19,445.00
(-17%)
₹16,204.00
Current price ₹16,204.00

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Book cover type: Hardcover
  • ISBN13: 9781603272667
  • Binding: Hardcover
  • Subject: Medical, Nursing and Health Sciences
  • Publisher: Springer Verlag
  • Publisher Imprint: Humana
  • Publication Date:
  • Pages: 250
  • Original Price: GBP 129.99
  • Language: English
  • Edition: N/A
  • Item Weight: 440 grams
  • BISAC Subject(s): Oncology / General and Pharmacology

From the Back Cover

Chemokine Receptors in Cancer summarizes the growing body of evidence that several chemokine receptors contribute to tumor behavior. Chemokine receptors were first identified on leukocytes and mediate directed migration of many host cells to sites of ligand expression. It is now well established that most malignant cells also express one or more chemokine receptor. This book describes our current understanding regarding how chemokine receptors contribute to tumor cell migration as well as cell survival and proliferation. The function of chemokine receptors expressed on host cells including antitumor immune effector cells as well as angiostatic and angiogeneic functions of chemokines acting on endothelial cells are described. The role of chemokine receptors that act as decoy receptors is also summarized. The therapeutic potential and challenges of targeting chemokine receptors or cognate ligands is also addressed.

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