• ISBN13: 9780824763992
• Binding: Hardcover
• Subject: Medical, Nursing and Health Sciences
• Publisher: T&F
• Publisher Imprint: Mar Dekker
• Publication Date: February 16, 2000
• Pages: 580
• Original Price: 123.0 GBP
• Language: English
• Edition: N/A
• Item Weight: 1000 grams

About the Book With bone metastases found to develop in more than half of patients with advanced cancers, this remarkable reference sheds much-needed light on the relation of various cancers-particularly breast and prostate cancer and multiple myeloma-to bone morbidity. The book addresses new therapies that can reduce the frequency of morbid skeletal events by as much as half.<br>Examines cancer's effects on bone tissue from pathophysiological, diagnostic, monitoring, and therapeutic points of view <br>Written by more than 40 international experts in the field, Tumor Bone Diseases and Osteoporosis in Cancer Patients<br><li>reviews the basics of bone physiology <br></li><li>investigates the propensity of breast cancer cells to metastasize in bone due primarily to the abundance of growth factors in the skeletal microenvironment-strongly supporting the seed-and-soil hypothesis of the metastatic process <br></li><li>discusses the efficacy of local radiotherapy and radioactive isotopes in treating bone metastases <br></li><li>covers endocrine and chemotherapy trials on patients with bone metastases <br></li><li>explores osteoclast activation and direct osteolytic effects of metastatic cancer cells <br></li><li>evaluates the noncytotoxic treatments of bisphosphonates as potent inhibitors of osteoclast-mediated bone resorption <br></li><li>assesses bisphosphonates as agents for ameliorating pain and preventing metastases in cancer patients <br></li><li>describes preventive therapy against osteoporosis <br></li><li>and more <br>Containing over 1700 references and more than 200 tables, drawings, and micrographs, Tumor Bone Diseases and Osteoporosis in Cancer Patients is a first-rank resource for medical, surgical, and clinical oncologists and radiotherapists, endocrinologists, internists, biologists, biochemists, and graduate and medical school students in these disciplines.</li>