Allgemeine Untersuchungsmethoden: Erster Teil
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zur zehnten Auflage. Analyse und quantitative Messung sind die Grundlagen einer jeden experimentellen Forschung. Die Untersuchung von biologischem Material bietet dabei besondere Schwierig- keiten, da die zu erfassenden Substanzen in einem ungemein kompliziert zusammen- gesetzten Milieu und zumeist nur in sehr geringf�gigen Konzentrationen vorliegen. Da- durch ergeben sich Fehlerm�glichkeiten in gro er Zahl und Anla zu mancherlei St�rungen. So ist die chemische Analyse von biologischem Material immer ein Sondergebiet geblieben, dessen Bearbeitung Spezialkenntnisse voraussetzt. Die pr�parative Darstellung der Bau- steine des menschlichen und des tierischen Organismus erfordert die Trennung zahlreicher Stoffe, die in ihren physikalischen und chemischen Eigenschaften einander sehr �hnlich sind; sie setzt daher die Beherrschung wirksamer Trennverfahren voraus. Die geringen Konzentrationen, in der viele biologisch wichtige Stoffe in den Organismen vorkommen, macht die Ausarbeitung hinreichend empfindlicher und spezifischer Bestimmungsver- fahren n�tig. So hat die biochemische Analytik unseren Besitz an Mikroverfahren au er- ordentlich bereichert. Im Jahre 1858, also vor fast 100 Jahren, hat HOPPE-SEYLER dieses Handbuch erstmalig herausgegeben. Seitdem war es f�r Generationen von Biochemikern, �rzten und Biologen unentbehrliches Handwerkszeug ihrer Arbeit, denn hier fanden sie alle Angaben �ber Gewinnung und Analyse der im tierischen Organismus unter normalen und pathologischen Verh�ltnissen vorkommenden chemischen Substanzen zusammengefa t. So erwies sich HOPPE-SEYLERS Handbuch bald als ein Standardwerk der Weltliteratur, so da bisher insgesamt in ziemlich regelm� igen Abst�nden 9 Auflagen, die letzte im Jahre 1924, erscheinen konnten. Schon 1893war der Stoff so angewachsen, da die 6. Auflage von HOPPE-SEYLER und THIERFELDER gemeinsam bearbeitet werden mu te. Die 9.
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