La maladie de Biermer: Du diagnostic au traitement
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La maladie de Biermer (MB), anciennement appel�e an�mie pernicieuse, est une pathologie auto-immune caract�ris�e par la destruction des cellules pari�tales gastriques et du facteur intrins�que, entra�nant une carence en vitamine B12. Cette vitamine �tant essentielle � la synth�se de l'ADN, son d�ficit provoque des anomalies h�matologiques, neurologiques et digestives.
Longtemps consid�r�e comme rare en Afrique, elle est d�sormais de plus en plus diagnostiqu�e au S�n�gal et en Afrique subsaharienne, avec des pr�sentations cliniques vari�es et parfois trompeuses. Sans traitement pr�coce, des complications graves peuvent survenir, notamment des s�quelles neurologiques ou un risque accru de cancer gastrique.
Le traitement repose sur une suppl�mentation en vitamine B12 (orale ou intramusculaire), permettant une r�gression des sympt�mes. Une surveillance r�guli�re est n�cessaire pour pr�venir les rechutes et les complications.
Cet ouvrage vise � am�liorer la connaissance de cette maladie, tout en alertant sur les diagnostics diff�rentiels pour �viter les erreurs.
Ndiaye, Fatou Samba Diago: - Fatou Samba Diago NDIAYE est Professeure titulaire, spécialiste en Hématologie clinique et Médecine interne. Ancienne Interne des Hôpitaux, elle dirige le service d'hématologie et le centre de greffe de moelle osseuse à l'Hôpital Dalal Jamm.
Madoky Magatte DIOP est Professeur titulaire en Médecine interne et AFS d'hépato-gastroentérologie. Chef du service de Médecine interne au CHREASN de Thiès et directeur du BESS de l'UIDT. Seynabou FALL est Professeur titulaire, spécialiste en Hématologie clinique et Médecine Interne, ancienne Interne des Hôpitaux de Dakar, praticienne au Service d'Hématologie Clinique et de Greffe de Moelle Osseuse à l'Hôpital Dalal Jamm.• Author(s): Clear | James • Publisher: Penguin • Publisher Imprint: Penguin Random House • Subject: General Books
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