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Rilascio Pulsatile Di Farmaci Modulato Dal Ritmo Circadiano by Dr R. Devi

Rilascio Pulsatile Di Farmaci Modulato Dal Ritmo Circadiano

by Dr R. Devi
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Book cover type: Paperback
  • ISBN13: 9786209561894
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edizioni Sapienza
  • Publisher Imprint: Edizioni Sapienza
  • Publication Date:
  • Pages: 72
  • Original Price: GBP 38.19
  • Language: Italian
  • Edition: N/A
  • Item Weight: 109 grams
  • BISAC Subject(s): Pharmacology

Un sistema di rilascio di farmaci pulsatile rilascia il farmaco in modo rapido e a raffica in un breve periodo di tempo, subito dopo una fase di ritardo programmabile. Ci sono molte situazioni in cui un farmaco deve essere rilasciato immediatamente (dopo lo scoppio del film ritardante) in un sito specifico. Queste situazioni, quindi, impongono la progettazione di un sistema a rilascio rapido ritardato. Questi sistemi sono adatti soprattutto per i farmaci che vengono metabolizzati in composti farmacologicamente attivi, per i farmaci che hanno un'emivita in vivo lunga e che mostrano una durata d'azione intrinsecamente prolungata, per i farmaci con un'emivita in vivo molto breve che richiedono una quantit� proibitiva di ingredienti attivi in forma di dosaggio, per i farmaci che sono richiesti in dosi elevate per l'effetto terapeutico e per i farmaci che sono richiesti in dosi molto basse. Inoltre, il rilascio ritardato pu� essere utilizzato anche per migliorare l'assorbimento, ridurre gli effetti collaterali e aumentare o diminuire la dose.

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