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Rola polimorfizmów genetycznych by Saleh A. S. Alabdulhadi

Rola polimorfizmów genetycznych

by Saleh A. S. Alabdulhadi
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Book cover type: Paperback
  • ISBN13: 9783330878440
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Wydawnictwo Nasza Wiedza
  • Publisher Imprint: Wydawnictwo Nasza Wiedza
  • Publication Date:
  • Pages: 168
  • Original Price: GBP 69.51
  • Language: Polish
  • Edition: N/A
  • Item Weight: 232 grams
  • BISAC Subject(s): General

Chemokiny przyczyniają się do astmatycznego zapalenia dr�g oddechowych, oddzialując na kom�rki śr�dblonka, eozynofile, bazofile i monocyty. Chemokiny to zlożona nadrodzina malych, wydzielanych bialek, kt�re początkowo scharakteryzowano na podstawie ich dzialania chemotaktycznego na r�żne leukocyty. Ekspresja wielu chemokin i ich rola w rekrutacji kom�rek jednojądrzastych zostala przeanalizowana w odniesieniu do wielu chor�b czlowieka o podlożu zapalnym, w tym stwardnienia rozsianego, przewleklego zapalenia oskrzeli, sarkoidozy, astmy i miażdżycy (Baggiolini i in., 2001). Możliwe powiązania między CCR5Δ32, CCR2V64I, CCR3Y17Y i promotorem RANTES-G403A a astmą i powiązanymi fenotypami zostaly zbadane w rodzinach wysokiego ryzyka.

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