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Zerebrale Effekte Der Hypothermen Extrakorporalen Zirkulation by Heidrun Stephan

Zerebrale Effekte Der Hypothermen Extrakorporalen Zirkulation

by Heidrun Stephan
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Book cover type: Paperback
  • ISBN13: 9783540529712
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Publication Date:
  • Pages: 78
  • Original Price: EUR 51.39
  • Language: German
  • Edition: N/A
  • Item Weight: 159 grams
  • BISAC Subject(s): Anesthesiology

Angaben über die Inzidenz neurologischer und psychischer Funktionsstörungen nach kardiopulmonalen Bypassoperationen reichen in verschiedenen klinischen Untersuchungen von 5 bis 64 %, wobei die Funktionsausfälle von leichten neurologischen Veränderungen bis zu zerebralen Infarkten reichen. Die Häufigkeit objektivierbarer Enzephalopathien wird 3 Monate nach kardiopulmonalem Bypass mit etwa 12 % angegeben. Vor diesem Hintergrund lassen sich aus der durch Hypothermie und kardiopulmonalem Bypass veränderten zerebralen Homöostase theoretische Überlegungen zur möglichen Ursache neurologischer und neuropsychologischer Störungen ableiten. Mit diesem Buch wird erstmals eine systematische Studie über das Verhalten von Hirndurchblutung, zerebralem Metabolismus, EEG-Verläufen und postoperativer Inzidenz neurologischer/neuropsychologischer Symptomatik nach pulsatiler und nichtpulsatiler Perfusionstechnik in Verbindung mit Hypothermie vorgelegt. Das Kernergebnis aus dieser Untersuchung zeigt, da ein nicht temperaturkorrigiertes Säure-Basen-Management während der extrakorporalen Zirkulation und Hypothermie für das Gehirn physiologischer ist und die Kopplung zwischen Hirnmetabolismus und Durchblutung unter diesen Bedingungen erhalten bleibt.

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