• ISBN13: 9781907568688
• Binding: Hardcover
• Subject: Bio-Science and Agriculture
• Publisher: Biohealthcare Pub.
• Publisher Imprint: Biohealthc
• Publication Date: January 1, 2012
• Pages: 200
• Original Price: USD 180.0
• Language: English
• Edition: N/A
• Item Weight: 454 grams
• BISAC Subject(s): Biomedical, Biotechnology, and Life Sciences / Developmental Biology

In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases and software available, before moving on to cover programming guidelines, including a specific case study on the use of C-It for in silico screening. The second half of the book offers a step-by-step guide to experimental validation concepts and procedures, as well as an overview of additional potential applications of this approach in the field of stem cells and tissue regeneration, before a concluding chapter summarises the concepts and theories presented.

Uchida, Shizuka: - Shizuka Uchida is a group leader in the Max-Planck Institute for Heart and Lung Research in Bad Nauheim, Germany. He is a trained bioinformatician and a developmental biologist with a specific focus on adult stem cell research, and has extensive experience in combining the power of computers and data mining methods with state-of-the-art experimental techniques.