Alternativa orale non invasiva alle terapie farmacologiche a base di insulina per il diabete

Name: Alternativa orale non invasiva alle terapie farmacologiche a base di insulina per il diabete
Brand: Edizioni Sapienza
SKU: 9786209893995
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ISBN13: 9786209893995
Binding: Paperback
Subject: N/A
Publisher: Edizioni Sapienza
Publisher Imprint: Edizioni Sapienza
Publication Date: April 1, 2026
Pages: 52
Original Price: USD 56.0
Language: Italian
Edition: N/A
Item Weight: 82 grams
BISAC Subject(s): Life Sciences / Biochemistry

About The Book

Le alternative terapeutiche non invasive per malattie che vanno dal diabete all'ipercolesterolemia sono all'avanguardia della ricerca. Sebbene siano state studiate molte vie di somministrazione non invasive, tra cui quella orale, buccale e cutanea, nessuna di esse � stata pienamente approvata per l'uso sui pazienti secondo gli standard della Food and Drug Administration (FDA) come alternativa all'attuale somministrazione di insulina tramite ago. 10 12 Questo libro si concentra su due nuovi sistemi di somministrazione orale di farmaci proteici: fosfato di α-Zr(IV) (α-ZrP)-proteina-ione metallico bivalente e fosfato di α-Zr(IV) (α-ZrP)-proteina-albumina sierica bovina (BSA) cationizzata. La glucosio ossidasi (GO) funge da proteina modello in questo libro per alternative non invasive all'abbassamento della glicemia nei diabetici di tipo I e II. Tuttavia, invece di incapsulare la GO, un trattamento farmacologico orale per il diabete, � possibile incapsulare anche proteine alternative come trattamenti farmacologici orali per disturbi quali l'ipercolesterolemia. Questo esperimento verifica quale versione ionizzata di BSA (BSA nativa-TEPA (-25), BSA-TEPA (0), BSA-TEPA (-13), BSA-TEPA (+5) o ioni metallici bivalenti (Mg (II), Ca (II) o Ba (II)) intercalato nello ZrP porta al massimo legame e rilascio di GO nella regione intestinale.

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