Approfondimenti su struttura, funzione, mutagenesi e riparazione del DNA

Name: Approfondimenti su struttura, funzione, mutagenesi e riparazione del DNA
Brand: Edizioni Sapienza
SKU: 9786630071795
Price: 5442.0 INR
Availability: InStock

by Heba Hassan , Mona El-Banna

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ISBN13: 9786630071795
Binding: Paperback
Subject: N/A
Publisher: Edizioni Sapienza
Publisher Imprint: Edizioni Sapienza
Publication Date: May 16, 2026
Pages: 64
Original Price: GBP 43.0
Language: Italian
Edition: N/A
Item Weight: 100 grams
BISAC Subject(s): Life Sciences / Biology

About The Book

Il DNA (acido desossiribonucleico) � la molecola fondamentale responsabile della memorizzazione, della trasmissione e dell'espressione dell'informazione genetica negli organismi viventi. Strutturalmente, il DNA � composto da due filamenti polinucleotidici antiparalleli disposti in una configurazione a doppia elica, stabilizzata dall'appaiamento complementare delle basi tra adenina e timina e guanina e citosina. Questa struttura altamente organizzata garantisce una replicazione accurata e un'eredit� affidabile delle informazioni genetiche attraverso le generazioni. Dal punto di vista funzionale, il DNA agisce come modello per l'espressione genica attraverso la trascrizione e la traduzione, dirigendo la sintesi di proteine che regolano la struttura cellulare, il metabolismo e l'attivit� biologica. Nonostante la sua stabilit�, il DNA � costantemente esposto a processi metabolici endogeni e a fattori ambientali che possono indurre mutazioni. Queste alterazioni possono presentarsi come mutazioni puntiformi, mutazioni frameshift o cambiamenti cromosomici pi� ampi, potenzialmente in grado di interrompere la funzione del gene. Le mutazioni del DNA svolgono un ruolo significativo nella variazione genetica, ma sono anche associate a numerose malattie umane, tra cui il cancro e i disturbi legati all'et�.

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