Das Mikroumfeld von Stammzellen und seine Auswirkungen auf die Behandlung von Leukämie

Name: Das Mikroumfeld von Stammzellen und seine Auswirkungen auf die Behandlung von Leukämie
Brand: Verlag Unser Wissen
SKU: 9786209829932
Price: 8360.0 INR
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by Malak Qattan

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ISBN13: 9786209829932
Binding: Paperback
Subject: N/A
Publisher: Verlag Unser Wissen
Publisher Imprint: Verlag Unser Wissen
Publication Date: March 31, 2026
Pages: 144
Original Price: GBP 66.0
Language: German
Edition: N/A
Item Weight: 200 grams
BISAC Subject(s): Life Sciences / Genetics & Genomics

About The Book

Die akute lymphoblastische Leuk�mie ist eine der h�ufigsten Formen der Leuk�mie bei Kindern. Obwohl bei der Heilungsrate bemerkenswerte Fortschritte erzielt wurden, besteht f�r einen Teil der Kinder nach wie vor das Risiko, aufgrund von Arzneimittelresistenzen oder toxischen Nebenwirkungen der Behandlung zu sterben. Glukokortikoide wie Dexamethason werden aufgrund ihrer proapoptotischen Wirkung regelm� ig in der Behandlung eingesetzt. J�ngste Studien haben die Rolle von Knochenmarkstammzellen bei der Entwicklung von Resistenzen, dem Versagen der Behandlung und dem daraus resultierenden Tod des Patienten hervorgehoben. In diesem Buch haben wir aufgezeigt, wie wichtig es ist, zu ber�cksichtigen, inwiefern sich eine kombinierte medikament�se Behandlung von einer Einzelmedikamententherapie unterscheidet und wie die Knochenmarkstammzellen die Arzneimittelresistenz beeinflussen k�nnen. Zusammenfassend l�sst sich sagen, dass unsere Erkenntnisse das Verst�ndnis der biologischen und molekularen Aspekte der Unterschiede zwischen empfindlichen und resistenten Zellen bei der akuten lymphoblastischen Leuk�mie sowie der Wirkung der Stammzellnische auf die Therapie verbessern k�nnen, was zu einer effizienteren und weniger toxischen Therapie beitragen kann.

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