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Der Experimentator: Microarrays by Hans-Joachim Müller, Thomas Röder

Der Experimentator: Microarrays

by Hans-Joachim Müller , Thomas Röder
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Book cover type: Paperback
  • ISBN13: 9783827414380
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Spektrum Akademischer Verlag
  • Publisher Imprint: Spektrum Akademischer Verlag
  • Publication Date:
  • Pages: 212
  • Original Price: EUR 28.03
  • Language: German
  • Edition: 2004
  • Item Weight: 445 grams
  • BISAC Subject(s): Life Sciences / Biology

Microrrays ist eine Sammelbezeichnung für moderne molekularbiologische Untersuchungssysteme, die die parallele Analyse von mehreren tausend Einzelnachweisen in einer geringen Menge biologischen Probenmaterials erlauben. DNA-Microrrays finden zunehmend Anwendung in der Genomanalyse, der Diagnostik und bei Untersuchungen in der differenziellen Genexpression. Die in der Entwicklung befindlichen Protein-Microrrays versprechen eine noch schnellere Vor-Ort-Analyse von Proben, da sie auf die oft notwendige Amplifikation genetischen Materials und die anschlie ende Hybridisierung verzichten und einen direkten Proteinnachweis erlauben. Dieses Buch widmet sich dem Thema Microarray mit verständlichen Erklärungen und einer übersichtlichen Darstellung der zur Zeit verfügbaren Instrumente und Biochips. Zielgruppe dieses Microarray-Buches sind alle mit wissenschaftlichen Methoden (z.B. Molekularbiologie, Proteinchemie) erfahrene Labormitarbeiter, Studenten und Wissenschaftler, die sich über die Microarray-Technologie informieren wollen. Es werden die unterschiedlichen Anforderungen für DNA- und Proteinchips in einzelnen Kapiteln aufgeführt. Der Leser erhält detaillierte Informationen, um ggf. ein eigenes Microarray-Labor einzurichten oder auszuweiten. Au erdem wird auf die Patent- und Internet-Recherche eingegangen und eine umfassende Literatur- sowie eine aktuelle Firmenliste beigefügt.

Dr. Hans-Joachim Müller war viele Jahre Kursleiter der Spektrum Akademie / Heidelberg für molekularbiologische Seminare und hat sein Wissen über die verschiedenen Anwendungen und Probleme der PCR in dem Spektrum-Methodenbuch 'PCR: Polymerase-Kettenreaktion' zusammengefasst. Herr Dr. Müller verfügt über eine langjährige Managementerfahrung in verschiedenen Life-Science-Unternehmen, wobei er für die F&E, Produktion sowie für den Verkauf von molekularbiologischen und diagnostischen Produkten verantwortlich war und ist. Hochschuldozent Dr. Thomas Roeder bekleidet derzeit eine Stiftungsdozentur für krankheitsrelevante Genomforschung am Biomedizinischen Forschungszentrum der Philipps Universität Marburg. Er beschäftigt sich mit der Entwicklung und Analyse neuer Tiermodelle für menschliche Erkrankungen sowie mit grundlegenden Aspekten des Nerven- und Immunsystems einfacher Modellorganismen.

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