Diversidade genética e estrutura populacional da cobaias domésticas
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Este trabalho teve como objetivo caracterizar a diversidade gen�tica e estabelecer as rela��es filogen�ticas entre as subpopula��es de cobaias da zona agroecol�gica com pluviometria bimodal dos Camar�es. Para tal, foi extra�do ADN gen�mico de 110 amostras de sangue de cobaias selecionadas com base na variabilidade fenot�pica, na disponibilidade dos criadores e na acessibilidade aos criadouros. O estudo foi realizado utilizando 16 marcadores microssat�lites SSR. Os principais resultados revelam um total de 11 alelos na popula��o. Cerca de 3% da diversidade gen�tica � atribu�vel � varia��o entre as popula��es e o restante deve-se �s diferen�as entre indiv�duos dentro da mesma popula��o. A taxa de homozigotos � elevada nesta popula��o e o coeficiente de consanguinidade � positivo. O conte�do m�dio de informa��o polim�rfica e o fluxo gen�tico muito elevado podem prenunciar uma perda de diversidade gen�tica que conduziria a uma redu��o das oportunidades futuras de melhoramento gen�tico da cobaias. A estrutura da popula��o, bem como a �rvore filogen�tica, permitiram evidenciar a exist�ncia de tr�s popula��es gen�ticas distintas.
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