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Heterocyclic Scaffolds in Drug Discovery by Shruti Kangad

Heterocyclic Scaffolds in Drug Discovery

by Shruti Kangad
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Book cover type: Paperback
  • ISBN13: 9786209848230
  • Binding: Paperback
  • Subject: N/A
  • Publisher: LAP Lambert Academic Publishing
  • Publisher Imprint: LAP Lambert Academic Publishing
  • Publication Date:
  • Pages: 84
  • Original Price: GBP 42.0
  • Language: English
  • Edition: N/A
  • Item Weight: 123 grams
  • BISAC Subject(s): Chemistry / Organic

Heterocyclic compounds represent a fundamental class of molecules in medicinal chemistry due to their structural diversity and broad spectrum of biological activities. These frameworks are integral to a majority of therapeutic agents and play a crucial role in drug discovery and development. Among them, 1,2,3-Triazole, Benzimidazole, Thiazole, and Benzo[g]quinoline derivatives have gained considerable importance as key pharmacophore exhibiting antimicrobial, anticancer, anti-inflammatory, and antidiabetic properties.This book provides a comprehensive overview of synthetic methodologies for the construction of these heterocyclic systems, covering both classical and modern strategies. Emphasis is given to reaction mechanisms, strategic transformations, and recent advances in efficient and sustainable synthesis. The biological significance of these compounds is further explored through structure-activity relationships, supported by in vitro and in silico studies.Overall, this work integrates synthetic and biological perspectives to support research in medicinal chemistry.

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