Nieinwazyjna, doustna alternatywa dla farmakoterapii cukrzycy opartej na insulinie

Name: Nieinwazyjna, doustna alternatywa dla farmakoterapii cukrzycy opartej na insulinie
Brand: Wydawnictwo Nasza Wiedza
SKU: 9786209896552
Price: 5022.0 INR
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ISBN13: 9786209896552
Binding: Paperback
Subject: N/A
Publisher: Wydawnictwo Nasza Wiedza
Publisher Imprint: Wydawnictwo Nasza Wiedza
Publication Date: April 1, 2026
Pages: 52
Original Price: USD 56.0
Language: Polish
Edition: N/A
Item Weight: 82 grams
BISAC Subject(s): Life Sciences / Biochemistry

About The Book

Nieinwazyjne alternatywne metody leczenia chor�b, od cukrzycy po hipercholesterolemię, znajdują się w czol�wce badań naukowych. Chociaż zbadano wiele nieinwazyjnych dr�g podawania lek�w, w tym doustną, śluz�wkową i sk�rną, żadna z nich nie zostala w pelni zatwierdzona do stosowania u pacjent�w zgodnie ze standardami Agencji ds. Żywności i Lek�w (FDA) jako alternatywa dla obecnego podawania insuliny za pomocą igly. 10 12 Niniejsza książka skupia się na dw�ch nowatorskich systemach doustnego podawania lek�w bialkowych: fosforan α-cyrkonu (IV) (α-ZrP)-bialko-jon metalu dwuwartościowego oraz fosforan α-cyrkonu (IV) (α-ZrP)-bialko-katjonizowana albumina surowicy bydlęcej (BSA). Oksydaza glukozowa (GO) sluży w niniejszej publikacji jako bialko modelowe dla nieinwazyjnych alternatyw obniżania poziomu cukru we krwi u chorych na cukrzycę typu I i II. Jednak zamiast enkapsulacji GO, doustnego leku przeciwcukrzycowego, można r�wnież enkapsulowac alternatywne bialka jako doustne leki na schorzenia takie jak hipercholesterolemia. W tym eksperymencie badano, kt�ra z jonizowanych wersji BSA (natywna BSA-TEPA (-25), BSA-TEPA (0), BSA-TEPA (-13), BSA-TEPA (+5) lub jon metalu dwuwartościowego (Mg (II), Ca (II) lub Ba (II)) wbudowany w ZrP zapewnia maksymalne wiązanie i uwalnianie GO w przewodzie pokarmowym.

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