Protein Misfolding Diseases

Name: Protein Misfolding Diseases
Brand: Academic Press
SKU: 9780443294143
Price: 9912.0 INR
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by Rossen Donev , Ajaz A. Bhat

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ISBN13: 9780443294143
Binding: Hardcover
Subject: N/A
Publisher: Academic Press
Publisher Imprint: Academic Press
Publication Date: December 15, 2025
Pages: 550
Original Price: USD 171.0
Language: English
Edition: N/A
Item Weight: 1066 grams
BISAC Subject(s): Life Sciences / Molecular Biology

About The Book

Protein Misfolding Diseases, delves into the intricate molecular mechanisms behind a class of devastating disorders caused by abnormal protein folding. This comprehensive book explores interesting and updated topics, including Protein misfolding in hemophilia, Characterizing Protein Misfolding: Inside and Out, Heat Shock proteins (HSPs) as chaperones for Oncogenesis, Protein Misfolding and Cancer: Molecular Insights and Future Perspectives, Proteostasis and Pathogenesis: Unraveling the Complexity of Protein Misfolding Disorders, Small molecule inhibitors targeting α-synuclein aggregation: Progress and future outlook, and much more.

Additional sections cover Chaperone Machinery in Neurodegeneration: A Spotlight on Protein Misfolding Diseases and Calpain- mediated proteolytic cleavage.

About The Author

Bhat, Ajaz A.: - Ajaz A. Bhat is a Senior Staff Scientist at Sidra Medicine, Qatar. He earned his PhD in Vaccine Immunology from AIIMS, New Delhi, and completed his postdoctoral fellowship at Vanderbilt University, Nashville, TN, USA, where his research was focused on tight junction proteins in colorectal cancer and bile acid-induced regulation of APE1/Ref1 in esophageal cancer. His current research is on cancer genetics, drug discovery, obesity, and diabetes.

Donev, Rossen: - Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.

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