Underutilized plants have the potential to be a tremendous source of bioactive compounds and are largely uncharted territory when it comes to the possibilities for application within modern nanomedicine. This book provides a thorough and current account on plant-based green nanoparticles produced from under-exploited plant resources and the ways in which they may be used in human health. The book presents the basics of nanotechnology that utilize plants as the basis for creating nanomaterials, including phytochemical profiling, the chemical synthesis pathways for both metals and alloys, and the Physical/Chemical Characteristics of the resulting nanoparticle materials. The beneficial potential of under-utilized plant derived nanoparticles in the treatment of many different types of diseases is also discussed in detail, including bacterial and fungal infections, Cancer, Diabetes, Obesity, and other constants and acute diseases. In-depth mechanistic describes are included to explain how these nanoparticles are able to provide anti-microbial and anti-cancer properties, through their cellular interactions. By unifying disparate research into one location, this book links basic science to applied research with good schematic figures and evidence-based discussion. It is intended for researchers, graduate students, academics and industry professionals working in the fields of Nanotechnology, Biotechnology, Pharmacology, and Biomedical Sciences, as a reference for Sustainable and Innovative Nanotherapeutics.
Dr. Eugenie Nepovimova currently serving as Assistant Professor at Department of Chemistry at University of Hradec Kralove. Dr. Nepovimova research focuses on drug design and development, in particular anti-aging drugs, novel potential therapeutics against neurodegenerative diseases and potential prophylactics and antidotes in case of organophosphate intoxication. Dr. Nepovimova served as guest editor in international journals. Currently Dr. Nepovimova is/was principal investigator: GA23-05857S and GA20-22037S (Czech Science Foundation), NW24J-04-00140 and NW26-04-00511 (Ministry of Health) and Project Excellence of University of Hradec Králové . She has also been a project team member: GA15-16701S, GA16-08554S, GA17-08596S, GA18-01734S (all Czech Science Foundation), NV15-30954A, NV19-09-00578 (both Ministry of Health) and CZ.02.1.01/0.0/0.0/16_017/0002311, CZ.02.1.01/0.0/0.0/16_025/0007444 (both OPVVV). Number of citations (total, without self-citations): 12 576/12 117 H-index: 55
Professor Kamil Kuca is a distinguished scholar who has held professorial positions and served as an invited or adjunct faculty member at esteemed academic institutions worldwide. His affiliations include the University of Defense in Brno, Czech Republic; Nanjing Agricultural University in Nanjing, China; University Hospital Hradec Kralove in Hradec Kralove, Czech Republic; Florida International University in Miami, USA; University of Hradec Kralove in Hradec Kralove, Czech Republic; Institute of Military Engineering in Rio de Janeiro, Brazil; Yangtze University in Jingzhou, China; University Technical Malaysia in Kuala Lumpur, Malaysia; Technical University Kosice in Kosice, Slovakia; and University of Granada in Granada, Spain. Professor Kuca's research encompasses diverse areas within pharmacology and toxicology, drug design and discovery, medical device development, pharmacoeconomics, food science, technology transfer, chemical and biological threat assessment, and military research. He has served as a principal investigator or team member on numerous national and international projects funded by prestigious organizations such as GACR, IGA MZ, MSMT, HORIZON, and NATO. With an extensive network of collaborators spanning across the globe, including Korea, India, Croatia, United Arab Emirates, China, Spain, Malaysia, and Brazil, Professor Kuca has contributed significantly to advancing scientific knowledge and fostering international cooperation. He has a H-index over 80 and has accumulated over 30,000 citations in the Web of Science. In 2021, he was honored as a Highly Cited Researcher by Clarivate Analytics. Recently he has 19 highly cited papers according to Clarivate Analytics. Additionally, Professor Kuca holds five patents and serves as a scientific advisor to several technology companies or co-owner of few startup companies, further demonstrating his leadership and expertise in the field.
Dr. Lukas Peter is a Vice-Dean for cooperation with industry at the Faculty of Material Science and Technology, Technical University of Ostrava in the Czech Republic. Dr. Peter's expertise lies in design and development of medical hardware and software like monitoring of cardiovascular system, biomechanics of cardiovascular system, signal processing in biomedicine etc. Currently under Dr. Peter's supervision his PhD students work on design and creation of a predictive model for evaluating the risk of treatment in chronic lymphocytic leukemia and design and development of a platform for reading and setting pacemaker firmware addressing for a pacemaker tester. Presently Dr. Peter is working on a project entitled Prototype - Innovative tester for automated testing of a dual-cavity external pacemaker granted by the Ministry of Industry and Trade of the Czech Republic.
