Biology of Bladder Cancer: From Molecular Insights to Clinical Strategies

Name: Biology of Bladder Cancer: From Molecular Insights to Clinical Strategies
Brand: Springer
SKU: 9783031685071
Price: 8006.0 INR
Availability: InStock

by Margaret A. Knowles , Lars Dyrskjøt

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ISBN13: 9783031685071
Binding: Paperback
Subject: N/A
Publisher: Springer
Publisher Imprint: Springer
Publication Date: January 1, 2024
Pages: 533
Original Price: EUR 108.99
Language: English
Edition: N/A
Item Weight: 933 grams
BISAC Subject(s): Oncology / General

About The Book

This book provides an update on the current understanding of various aspects of bladder cancer biology and introduces clinical manifestations together with current and novel treatment aspects.

Key concepts covered include epidemiology and genetic predisposition to bladder cancer, insights into the mutational events and molecular pathogenesis of bladder cancer, detailed analyses of tumor subtypes, and references to common experimental models used in the study of bladder cancer. The book addresses critical issues such as the molecular features that contribute to the development of bladder cancer, the impact of the tumor microenvironment on disease progression, and the potential of novel urine- and blood-based biomarkers for diagnosis and treatment. Innovative therapeutic applications are also explored, including targeting immune checkpoints and personalized medicine approaches.

Aimed at early career and experienced researchers or clinicians alike, this volume provides an interdisciplinary understanding of bladder cancer. Delving into the biology, pathology, and clinical aspects of the disease, it serves as an indispensable resource for understanding bladder cancer's complexity.

About The Author

Maggie Knowles, PhD is Emeritus Professor of Experimental Cancer Research at the University of Leeds in the UK. She has worked on bladder cancer for more than forty years with the goal of improving disease management through molecular studies. Her work has included identification of key genes involved in the development of bladder cancer, sub-classification of non-invasive tumours through genomic and transcriptional analyses and development of in vitro models for preclinical validation of potential therapeutic targets and improved understanding of gene function. Her extensive publications and leadership roles have played an important part in shaping bladder cancer research over the past two decades.

Lars Dyrskjøt, PhD, is a Professor of Molecular Medicine at Aarhus University in Denmark, where he leads a team focused on translational bladder cancer research. His work has greatly enhanced understanding of the disease's molecular pathogenesis, especially through the identification of prognostic and predictive biomarkers in early-stage bladder cancer, and the innovative use of liquid biopsies for monitoring and guiding treatment in advanced bladder cancer. With his extensive publications and leadership roles in international cancer research initiatives, Prof. Dyrskjøt plays a crucial role in advancing the global discourse on bladder cancer.

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