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Chirurgisches Forum'80: Für Experimentelle Und Klinische Forschung, 97. Kongreß Der Deutchen Gesellschaft Für Chirurgie, München, 14. Bis 17. Mai 1980

by F. Linder , H. Junghanns , H. D. Röher
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Current price ₹3,776.00
Original price ₹5,808.00
Original price ₹5,808.00
Original price ₹5,808.00
(-35%)
₹3,776.00
Current price ₹3,776.00

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Book cover type: Paperback
  • ISBN13: 9783540100355
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Publication Date:
  • Pages: 336
  • Original Price: EUR 51.39
  • Language: German
  • Edition: N/A
  • Item Weight: 581 grams
  • BISAC Subject(s): Surgery / Neurosurgery

22 polytraumatisierte und septische Patienten einer Intensiv- station wurden im Rahmen einer Doppelblindstudie mit Pirenzepin bzw. Placebo behandelt. Alle Patienten wurden wahrend des Beob- achtungszeitraumes in 14 Tagen dreimal endoskopiert. Ohne Pro- phylaxe waren 100% StreB-Lasionen zu beobachten, 60% wiesen Blu- tungen auf. Eine prophylaktische, intravenose Pirenzepin-Gabe hatte einen eindeutig protektiven Effekt im Hinblick auf die StreB-Blutung, Anzahl und Schweregrad der StreB-Lasionen. Summary Twenty-two severely ill patients with multinle injuries and sepsis were treated with IV pirenzepin or placebo 3 x 10 mg per day in the frame of the double-blind study. All the patients were examined three times with endoscopy during the 14-day ob- servation period. In 100% of cases without prophylactic treat- ment, stress lesions were observed, 60% of these cases had bleeding. A prophylactic IV pirenzepin application had an un- mistakable protective effect regarding the stress bleeding, number and degree of stress lesions. Literatur 1. BRODIE, D.A.: Experimental peptic ulcer. Gastroenterology 55, 125-134 (1968) 2. EINIG, D.: Ein neuer Sekretionshemmer. Ergebnisse einer Wir- kungs- und Vertraglichkeitsprufung mit Gastrozepin. Therapie- woche 27,1630-1638 (1977) 3. HASTINGS, P.R., SKILLMAN, J.J., BUSHNELL, L.J. et al.: Antacid titration in the prevention of acute gastrointestinal bleeding: a controlled randomized trial in 100 critically ill patients.

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