Histochemie: Einführung in Grundlagen Und Prinzipien Der Methoden
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Die Histochemie hat ein fast un�bersehbares Arsenal von Methoden zur Stoff- ortung im histologischen Pr�parat bereitgestellt. Die histochemische Grundlagen- forschung entwickelt in rascher Folge weitere spezielle Verfahren, die f�r die topo- chemische Analyse licht- und elektronenmikroskopischer Objekte eingesetzt werden k�nnen. Die beeindruckenden M�glichkeiten histochemischer Gewebsuntersuchung haben zu breiter Anwendung auf den verschiedensten Gebieten, vor allem auch in der klinischen Medizin, gef�hrt. Dies hat zur nat�rlichen Folge, da h�ufig histochemisch zun�chst unerfahrenes technisches Hilfspersonal mit der Pr�paratherstellung befa t ist und da auch die wissenschaftliche Interpretation der Ergebnisse oft auf unzu- reichenden Erfahrungsgrundlagen erfolgt. So erkl�rt es sich, da so viele histoche- mische Befunde ver�ffentlicht werden, die der Kritik nicht standhalten. Aus vielf�ltigen Erfahrungen bei der Zusammenarbeit auf dem Gebiet der ange- wandten Histochemie ergibt sich, da insbesondere der Mediziner vielen z. T. elemen- taren Schwierigkeiten gegen�bersteht. Das exakte Nacharbeiten von Methoden anhand der ausgezeichneten Werke, die f�r diesen Zweck bereits zur Verf�gung stehen, gen�gt offensichtlich nicht, die histochemische Praxis auf eine sichere Grund- lage zu stellen. Von dem Gedanken ausgehend, da Verst�ndnis f�r den Mechanismus der einzelnen speziellen histochemischen Reaktionen zwar selbstverst�ndlich notwendig, aber allein nicht ausreichend ist, da vielmehr Einsicht in die allgemeinen Grund- prinzipien histologisch-histochemischer Arbeitsweisen geweckt werden m�sse, wurde das vorliegende Werk konzipiert. Der Akzent der Darstellung liegt auf der Behand- lung der methodischen Grundm�glichkeiten. DerenSystematisierung f�hrt zu einer Methodologie im eigentlichen Sinn, in deren Rahmen jede spezielle Methode die Wertigkeit einer Anwendung oder eines Beispiels hat.
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