Immunological Challenges in Organ Transplantation: A Comprehensive Case-Based Approach
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Chapter1.. HLA Structure, Function, and Clinical Implications in Transplantation: A Case-Based and Molecular Perspective.- Chapter2.. Nutrition and immunological challenges in transplantation.- Chapter3.. Why we require immunological workup- A patient-centered, case-based approach.- Chapter4.. HLA loci and typing in solid organ transplantation - A case-based approach to HLA typing and applications in clinical practice.- Chapter5.. Eplets and Epitopes in transplantation.- Chapter6.. Virtual cross match in kidney transplantation.- Chapter7.. Molecular Biomarkers to Assess Kidney Allograft Status.- Chapter8.. Approach to an unsensitised patient awaiting first renal transplant – Algorithms of choice.- Chapter9.. A case based approach to the sensitised recipient with DSA on the SAB to the proposed donor.- Chapter10.. Non-HLA Antibodies in Kidney Transplantation.- Chapter11.. A persistent CDC positive cross-match in a patient awaiting transplant - Variations of the CDC and comparisons across platforms.- Chapter12.. Kidney Transplant Rejection: T-Cell and Antibody-Mediated Rejection.- Chapter13.. Immunology of ABO incompatible transplantation.- Chapter14.. Approach to Lung transplant immunology.- Chapter15.. Immunology of heart transplantation.- Chapter16.. Approach to Liver Transplant: The Immunomodulatory Role of the Liver and Its Mesenchymal Stem Cells.- Chapter17.. Challenges in Bone Marrow Transplant: Tale of Two Women.- Chapter18.. Immunological Evaluation and Management of pediatric kidney transplant recipients.- Chapter19.. An approach to rational therapeutics by navigating pathophysiology and evidence for complex clinical situations.- Chapter20.. Immunological challenges in Xenotrasplantation.- Chapter21.. Conclusions, Recommendations and guidelines for immunological evaluation of a transplant recipient.
Prof. Georgi Abraham, MD, MRCP, FRCP, is a practicing and academic kidney specialist who has published extensively on kidney disease, hemodialysis, peritoneal dialysis, and transplantation. He is the founder trustee of the Tanker Foundation, a charity for kidney disease patients. He has received several prestigious awards, including a International Distinguished Medal in Nephrology from NKF USA, D G Oreopoulos Lifetime Achievement award for his contribution to peritoneal dialysis from International Society for Peritoneal dialysis, Roscoe Robinson award from International Society of Nephrology and PACES champion award from Federation of Royal college of Physicians of UK. He has also published extensively on transplantation and immunosuppressive drugs with 360 publications,34 book chapters and many orations in India and aboard. He served as the president of the Indian Society of Transplantation from 2022 to 2023.
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