Pathologische Erregbarkeit Des Nervensystems Und Ihre Behandlung: Membranfunktion, Neurotransmitter Und Hirnpeptide Bei Epilepsien, Extrapyramidalmoto
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Tremor ist ein unvermeidliches Nebenprodukt der Muskeltätigkeit. Die- ser physiologische Tremor hat, ähnlich dem normalen EEG, ein charak- teristisches Frequenzspektrum. Erkrankungen des extrapyramidal-moto- rischen Systems führen durch eine pathologische Synchronisation moto- rischer Einheiten zu verstärkten Tremoren, die ebenfalls typische Spek- tren zeigen. Da sich die Innervation des Muskels bei allen zentral- oder periphermotorischen Störungen ändert, führt dies notwendig auch zu entsprechenden Änderungen der Tremorspektren. Somit zeigen auch die- jenigen Läsionen des motorischen Systems pathologische Tremorspektren, bei denen die Tremoramplituden normal sind und deshalb klinisch nicht als krankhaft imponieren. Literatur 1. Allum JHJ, Dietz V, Freund H-J (1978) Neuronal mechanisms under- lying physiological tremor. J Neurophysiol 41: 557-571 2. Altenburger H (1937) Elektrodiagnostik. In: Bumke und Förster (Hrsg) Hb der Neurologie . Springer, Berlin, Bd. 3, S 747-1086 3. Charcot JM (1875) Lecons sur les maladies du systeme nerveux faites ala Salpetriere, Bd. 2. Delahaye, Paris 4. Creed RS, Denny-Brown D, Eccles JC, LiddeI EGT, Sherrington CS (1932) Reflex activity of the spinal cord. Clarendon Press S. Dietz V, Bischofsberger E, Wita C, Freund H-J (1976) Correlation between discharges of two simultaneously recorded motor units and physiological tremor. Elektroenceph clin Neurophysiol 40: 97-105 6. Förster 0 (1936) Symptomatologie der Erkrankungen des Rückenmarks und seiner Wurzeln. In: Bumke und Förster (Hrsg) Hb der Neurolo- gie. Springer, Berlin, Bd. 5, S 1-403 7. Freund H-J, Dietz V (1978) The relationship between physiological and pathological tremor. In: Desmedt JE (ed) Physiological tremor, pathological tremors and clonus. Prog clin Neurophysiol Bd. 5.
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