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The Biological Role of Small Leucine-Rich Proteoglycans (SLRPs) in Matrix Homeostasis and Diseases by Polly Lama

The Biological Role of Small Leucine-Rich Proteoglycans (SLRPs) in Matrix Homeostasis and Diseases

by Polly Lama
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Book cover type: Hardcover
  • ISBN13: 9789819678891
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Publication Date:
  • Pages: 209
  • Original Price: EUR 141.69
  • Language: English
  • Edition: N/A
  • Item Weight: 457 grams
  • BISAC Subject(s): Life Sciences / Cell Biology

Ch 1 The family, structure, and functions of small leucine rich proteoglycans (SLRPs).-Ch 2 Diseases of the matrix and the role of SLRPs in inflammatory catabolism.- Ch  3 Regulatory role and significance of class I SLRPs: Biglycan, Decorin and Asporin.- Ch 4 Regulatory role and significance of Class II SLRP’s: Fibromodulin, Lumican, Osteoadherin, PRELP, and keratocan.- Ch 5 Regulatory role and significance of Class III SLRPs: Osteoglycin, Epiphycan and Opticin.- Ch 6 Regulatory role and significance of Class IV SLRPs: Tsukushi, Chondroadherin and Nyctalopin.- Ch 7 Regulatory role and significance of Class V SLRPs: Podocan and Podocan-like protein-1.- Ch 8 Biological basis behind molecular fragmentation of SLRPs as DAMPs.- Ch 9 SLRPs and its therapeutic relevance.- Ch 10: Critical conclusive overview: SLRPs as DAMPs.

Dr. Polly Lama completed her Ph.D. in molecular matrix degeneration in cartilage diseases from the University of Bristol, United Kingdom, and she has worked as a post-doctorate research fellow at McGill University, Canada. Dr. Lama is currently working as a professor of anatomy, quality assurance in charge, and executive coordinator at Sikkim Manipal University (SMU), Sikkim, India. She has published several papers in peer-reviewed national and international journals including Cell Death and Discovery, Nature, Artificial Intelligence on Medical Data, Nature, Bone and Joint Surgery Journal, and the Journal of Anatomy; received many awards for her contribution to research and teaching in her area of expertise. Dr. Lama is a reviewer as well as an editorial member of the Springer Nature BMC Musculoskeletal Diseases, the Experimental Molecular Medicine, the Nature Journal, and Journal of Cellular and Molecular Medicine.

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