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Introduction to Population Pharmacokinetic/Pharmacodynamic Analysis with Nonlinear Mixed Effects Models
Joel S. Owen
Hardcover
• Author(s): Joel S. Owen • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThis book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokin...
View full detailsAdverse Drug Reactions: A Practical Guide to Diagnosis and Management
Christian Benichou
Paperback
• Author(s): Christian Benichou • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyReviews the biochemical and physiological abnormalities in each of the body's organ systems, enabling investigators to decide if the problem is of ...
View full detailsEarly Drug Development: Strategies and Routes to First-In-Human Trials
Mitchell N. Cayen
Hardcover
• Author(s): Mitchell N. Cayen • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThe focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Developmen...
View full detailsAn Introduction to Statistics in Early Phase Trials
Steven Julious
Hardcover
• Author(s): Steven Julious • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyAll new medicines and devices undergo early phase trials to assess, interpret and better understand their efficacy, tolerability and safety. An Introdu...
View full detailsTherapeutic Targets: Modulation, Inhibition, and Activation
Luis M. Botana
Hardcover
• Author(s): Luis M. Botana • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThe Latest Applications For Cellmechanism Research in Drug Discovery Designed to connect research on cell mechanisms with the drug discovery process, T...
View full detailsCase Studies in Modern Drug Discovery and Development
Xianhai Huang
Hardcover
• Author(s): Xianhai Huang • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyLearn why some drug discovery and development efforts succeed . . . and others fail Written by international experts in drug discovery and development,...
View full detailsApplications of Microdialysis in Pharmaceutical Science
Tung-Hu Tsai
Hardcover
• Author(s): Tung-Hu Tsai • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyDiscover new and emerging applications for microdialysis in drug evaluation Microdialysis is a highly valuable sampling tool that can be used in vivo to ...
View full detailsDrug Benefits and Risks: International Textbook of Clinical Pharmacology
Chris J. Van Boxtel
Hardcover
• Author(s): Chris J. Van Boxtel • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThis is an inclusive reference exploring the scientific basis and practice of drug therapy. The key concept is to look at the balance between the ...
View full detailsMolecular Pharmacology: From DNA to Drug Discovery
John Dickenson
Hardcover
• Author(s): John Dickenson • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThis textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug tar...
View full detailsDevelopment of Therapeutic Agents Handbook
Shayne Cox Gad
Hardcover
• Author(s): Shayne Cox Gad • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyA comprehensive look at current drug discovery and development methods—and the roadmap for the future Providing both understanding and guidance in cha...
View full detailsPredictive Approaches in Drug Discovery and Development: Biomarkers and in Vitro/In Vivo Correlations
J. Andrew Williams
Hardcover
• Author(s): J. Andrew Williams • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyPractical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and developmen...
View full detailsPharmacogenetics and Individualized Therapy
Anke-Hilse Maitland-Van Der Zee
Hardcover
• Author(s): Anke-Hilse Maitland-Van Der Zee • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThis resource provides thorough coverage of pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practice. I...
View full detailsLabel-Free Technologies for Drug Discovery
Matthew Cooper
Hardcover
• Author(s): Matthew Cooper • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyOver the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be use...
View full detailsPackaging Technology and Engineering
Dipak Kumar Sarker
Hardcover
• Author(s): Dipak Kumar Sarker • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyCovers chemistry, physics, engineering, and therapeutic aspects of packaginguniversal to pharmaceutical, medical, and food applications This book ...
View full detailsSystems Biology in Drug Discovery and Development
Daniel L. Young
Hardcover
• Author(s): Daniel L. Young • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThe first book to focus on comprehensive systems biology as applied to drug discovery and development Drawing on real-life examples, Systems Biology ...
View full detailsPharmaceutical Data Mining: Approaches and Applications for Drug Discovery
Konstantin V. Balakin
Hardcover
• Author(s): Konstantin V. Balakin • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyLeading experts illustrate how sophisticated computational data mining techniques can impact contemporary drug discovery and development In the...
View full detailsDrug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools
Sean Ekins
Hardcover
• Author(s): Sean Ekins • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyDrug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools covers key emerging technologies in pharmaceutical R & D and how they h...
View full detailsBenefit-Risk Appraisal of Medicines: A Systematic Approach to Decision-Making
Filip Mussen
Hardcover
• Author(s): Filip Mussen • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyBenefit-risk assessment is at the centre of the approval process for every new medicine. The ability to assess the risks of a new medicine accurately and...
View full detailsDrug Delivery Applications of Noninvasive Imaging: Validation from Biodistribution to Sites of Action
Chun Li
Hardcover
• Author(s): Chun Li • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyCost-effective strategies for designing novel drug delivery systems that target a broad range of disease conditions In vivo imaging has become an important to...
View full detailsDrug Discrimination: Applications to Medicinal Chemistry and Drug Studies
Richard A. Glennon
Hardcover
• Author(s): Richard A. Glennon • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyDrug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacologic...
View full detailsAdvanced Drug Delivery
Ashim Mitra
Hardcover
• Author(s): Ashim Mitra • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyProvides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, present...
View full detailsDendrimer-Based Drug Delivery Systems: From Theory to Practice
Yiyun Cheng
Hardcover
• Author(s): Yiyun Cheng • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThe opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in dr...
View full detailsDrug Discovery: Practices, Processes, and Perspectives
Jie Jack Li
Hardcover
• Author(s): Jie Jack Li • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologySets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pi...
View full detailsProtein and Peptide Mass Spectrometry in Drug Discovery
Michael L. Gross
Hardcover
• Author(s): Michael L. Gross • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThe book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical ...
View full detailsLead Generation Approaches in Drug Discovery
Zoran Rankovic
Hardcover
• Author(s): Zoran Rankovic • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyAn integrated overview of modern approaches to lead discovery Lead generation is increasingly seen as a distinct and success-determining phase of the ...
View full detailsOral Bioavailability: Basic Principles, Advanced Concepts, and Applications
Ming Hu
Hardcover
• Author(s): Ming Hu • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyUnderstand and assess the design, delivery, and efficacy of orally administered drugs A practical guide to understanding oral bioavailability, one of the majo...
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G Protein-Coupled Receptors: Molecular Pharmacology from Academic Concept to Pharmaceutical Research
G Protein-Coupled Receptors: Molecular Pharmacology from Academic Concept to Pharmaceutical Research
Georges Vauquelin
Hardcover
• Author(s): Georges Vauquelin • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyG protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging ...
View full detailsDrug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications
Claudiu T. Supuran
Hardcover
• Author(s): Claudiu T. Supuran • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyBrings together functional and structural informationrelevant to the design of drugs targeting zinc enzymes The second most abundant transition el...
View full detailsFlow Cytometry in Drug Discovery and Development
Virginia Litwin
Hardcover
• Author(s): Virginia Litwin • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThis book covers the unique application of flow cytometry in drug discovery and development. The first section includes two introductory chapters, one...
View full detailsTopical and Transdermal Drug Delivery: Principles and Practice
Heather A. E. Benson
Hardcover
• Author(s): Heather A. E. Benson • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyPractical drug development approaches presented by leading experts Designed to support the development of new, effective therapeutics, Topical a...
View full detailsPharmacology for the Health Care Professions
Christine M. Thorp
Hardcover
• Author(s): Christine M. Thorp • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyPharmacology for the Health Care Professions is an accessible introduction to the pharmacology necessary for health care professionals training to ...
View full detailsBiological Drug Products: Development and Strategies
Wei Wang
Hardcover
• Author(s): Wei Wang • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyTested and proven solutions to the challenges of biological drug product development Biological drug products play a central role in combating human diseases...
View full detailsMedicinal Chemistry of Nucleic Acids
Li-He Zhang
Hardcover
• Author(s): Li-He Zhang • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyComplete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with expertis...
View full detailsEvaluation of Drug Candidates for Preclinical Development: Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology
Chao Han
Hardcover
• Author(s): Chao Han • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyEmphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the "right" drug candi...
View full detailsPhysicochemical and Biomimetic Properties in Drug Discovery: Chromatographic Techniques for Lead Optimization
Klara Valko
Hardcover
• Author(s): Klara Valko • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyDemonstrating how and why to measure physicochemical and biomimetic properties in early stages of drug discovery for lead optimization, Physicochemical an...
View full detailsAdvances in Drug Discovery Techniques
Alan L. Harvey
Hardcover
• Author(s): Alan L. Harvey • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThis invaluable volume serves as a guide to up-to-the-minute techniques for the discovery and evaluation of pharmacologically active compounds for ther...
View full detailsSelection, Preparation and Pharmacological Evaluation of Plant Material, Volume 1
Elizabeth M. Williamson
Paperback
• Author(s): Elizabeth M. Williamson • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyLaboratory protocols for pharmacological investigation of plant material Pharmacological Methods in Phytotherapy Research, Vol. 1: Selection, ...
View full detailsCollaborative Innovation in Drug Discovery: Strategies for Public and Private Partnerships
Rathnam Chaguturu
Hardcover
• Author(s): Rathnam Chaguturu • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyCan academia save the pharmaceutical industry? The pharmaceutical industry is at a crossroads. The urgent need for novel therapies cannot stem the ...
View full detailsPharmaceutical Biotechnology: Concepts and Applications
Gary Walsh
Hardcover
• Author(s): Gary Walsh • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyPharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving...
View full detailsPharmaceutical Biotechnology: Concepts and Applications
Gary Walsh
Paperback
• Author(s): Gary Walsh • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyPharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving...
View full detailsDetection and Quantification of Antibodies to Biopharmaceuticals: Practical and Applied Considerations
Michael G. Tovey
Hardcover
• Author(s): Michael G. Tovey • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThe definitive book on the neutralization of recombinant biopharmaceuticals Recombinant biopharmaceuticals are an important tool for treating a range...
View full detailsMonoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer
Raymond M. Reilly
Hardcover
• Author(s): Raymond M. Reilly • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyOncology Book of 2011, British Medical Association's Medical Book Awards Awarded first prize in the Oncology category at the 2011 BMA Medical Book...
View full detailsPediatric Nonclinical Drug Testing: Principles, Requirements, and Practices
Alan M. Hoberman
Hardcover
• Author(s): Alan M. Hoberman • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThis book explains the importance and practice of pediatric drug testing for pharmaceutical and toxicology professionals. It describes the practical ...
View full detailsPhytochemical Drug Discovery for Central Nervous System Disorders: Biochemistry and Therapeutic Effects
Chukwuebuka Egbuna
Hardcover
• Author(s): Chukwuebuka Egbuna • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyPHYTOCHEMICAL DRUG DISCOVERY FOR CENTRAL NERVOUS SYSTEM DISORDERS Understand herbal and plant-based treatments for chronic disorders with this grou...
View full detailsAnimal Models for Development of Cancer Immunotherapy
Seng-Lai Tan
Hardcover
• Author(s): Seng-Lai Tan • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyAnimal Models for the Development of Cancer Immunotherapy Provides readers with a clear understanding of the value and challenges of using common and eme...
View full detailsAntibiotic Drug Resistance
Jose-Luis Capelo Martinez
Hardcover
• Author(s): Jose-Luis Capelo Martinez • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThis book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate re...
View full detailsEmerging Technology Platforms for Stem Cells
Uma Lakshmipathy
Hardcover
• Author(s): Uma Lakshmipathy • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThis book focuses on practical applications for using adult and embryonic stem cells in the pharmaceutical development process. It emphasizes new tec...
View full detailsPeripheral Receptor Targets for Analgesia: Novel Approaches to Pain Management
Brian E. Cairns
Hardcover
• Author(s): Brian E. Cairns • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyA unique reference on peripheral pain receptor mechanisms While considerable advances have been made on pharmacotherapies for many chronic disease st...
View full detailsGenotoxic Impurities: Strategies for Identification and Control
Andrew Teasdale
Hardcover
• Author(s): Andrew Teasdale • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThis book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and ...
View full detailsIntegrated Cardiac Safety: Assessment Methodologies for Noncardiac Drugs in Discovery, Development, and Postmarketing Surveillance
J. Rick Turner
Hardcover
• Author(s): J. Rick Turner • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThe serious nature of cardiovascular adverse drug reactions occurring in patients makes assessment of a drug's cardiac safety profile a high priority d...
View full detailsValidation of Cell-Based Assays in the GLP Setting: A Practical Guide
Uma Prabhakar
Hardcover
• Author(s): Uma Prabhakar • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThe use of cell-based assays within pharmaceutical and biotechnology companies is driven in large part by the need to evaluate the plethora of drug targ...
View full detailsCardiovascular Diseases: From Molecular Pharmacology to Evidence-Based Therapeutics
Y. Robert Li
Hardcover
• Author(s): Y. Robert Li • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyWritten in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, as ...
View full detailsGPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions
Annette Gilchrist
Hardcover
• Author(s): Annette Gilchrist • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyG protein-coupled receptors (GPCRs) are a large protein family of transmembrane receptors vital in dictating cellular responses. GPCRs are involved ...
View full detailsIminosugars: From Synthesis to Therapeutic Applications
Philippe Compain
Hardcover
• Author(s): Philippe Compain • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyIminosugars form undoubtedly the most attractive of carbohydrate mimics reported so far. In these structures, the substitution of the endocyclic oxyg...
View full detailsCarbohydrate Recognition: Biological Problems, Methods, and Applications
Binghe Wang
Hardcover
• Author(s): Binghe Wang • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyThis book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the develop...
View full detailsPharmaceutical Chemistry: Therapeutic Aspects of Biomacromolecules
Christine Bladon
Hardcover
• Author(s): Christine Bladon • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyProviding a broad introduction to the growing field, this book explores the way in which peptides, proteins, nucleic acids and carbohydrates used the...
View full detailsPharmaceutical Chemistry: Therapeutic Aspects of Biomacromolecules
Christine Bladon
Paperback
• Author(s): Christine Bladon • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyProviding a broad introduction to the growing field, this book explores the way in which peptides, proteins, nucleic acids and carbohydrates used the...
View full detailsGuidebook for Drug Regulatory Submissions
Sandy Weinberg
Hardcover
• Author(s): Sandy Weinberg • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyDestined to become every regulatory director's essential desktop companion Professionals working to submit major documents to the Food and Drug Admini...
View full detailsDisease Mapping with Winbugs and Mlwin
Andrew B. Lawson
Hardcover
• Author(s): Andrew B. Lawson • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyDisease mapping involves the analysis of geo-referenced disease incidence data and has many applications, for example within resource allocation, clu...
View full detailsDevalued and Distrusted: Can the Pharmaceutical Industry Restore Its Broken Image?
John L. Lamattina
Paperback
• Author(s): John L. Lamattina • Publisher: Wiley • Publisher Imprint: Wiley • BISAC: PharmacologyAn expert's view on solving the challenges confronting today's pharmaceutical industry Author John LaMattina, a thirty-year veteran of the pharmaceu...
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