Adjuvante Zytostatische Chemotherapie: Zytostatische Therapie ALS Rezidivprophylaxe?
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Das Konzept der experimentellen Onkologie, schon im Stadium der Mikrometa- stasierung zytostatischer Medikamente einzusetzen, wird derzeit bei verschiede- nen menschlichen Tumoren auf breiter Basis untersucht. Damit hat die Frage nach den Erfolgsaussichten und der Indikationsstellung fur adjuvante zytostati- sche Therapie in den letzten Jahren an besonderer Aktualitat gewonnen. Bei einigen Erkrankungen, die dem osteogenen und Ewing-Sarkom, Wilmstumoren, dem embryonalen Rhabdomyosarkom, manchen Hodentumoren u. a., sind Erfolgsaussichten dieses Vorgehens deutlich, bei weit haufigeren Neoplasien, wie dem Mammacarcinom, Ovarialcarcinom, bei malignen Lymphomen u. a., wird die Indikationsstellung lebhaft diskutiert. Die arztliche Entscheidung zu dieser Therapieform wird durch die Diskussion in der bffentlichkeit keineswegs und laBt zusammenfassende, kritische Informationen zu diesem erleichtert Thema besonders suchen. Die gemeinsame Tagung der Deutschen und bsterreichischen Gesellschaft fUr Hamatologie und Onkologie im November 1977 in Linz gab Gelegenheit, die Grundlagen adjuvanter zytostatischer Therapien und den derzeitigen Stand ihrer praktischen Anwendung zu diskutieren, wobei auch Gefahren und Nebenwir- kuilgen breiter Raum gegeben wurde. Urn der Wichtigkeit der Frage gerecht zu werden und die Ergebnisse moglichst auf den letzten Stand zu bringen, konnten fur die Publikation zusatzliche Referenten mit internationalem Ansehen gewonnen werden. Die wichtigsten Diskussionsbemerkungen wurden ebenfalls aufgenommen. Sie mochten dokumentieren, wie viele Fragen noch offen sind und weiterer gemeinsamer Anstrengungen bedurfen. Die Publikation dieses Bandes wurde durch gemeinsame Bemuhungen unserer Mitarbeiter in Linz, St. Gallen und Innsbruck ermoglicht, denen wir besonders verpflichtet sind. Frau Doktor G. Kratzer und Herr Oberarzt Dr. H.
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