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Adjuvantes de vacinas à base de plantas by Gupta, Amit

Adjuvantes de vacinas à base de plantas

by Amit Gupta
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Book cover type: Paperback
  • ISBN13: 9786208991241
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edicoes Nosso Conhecimento
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Publication Date:
  • Pages: 72
  • Original Price: GBP 31.23
  • Language: Portuguese
  • Edition: N/A
  • Item Weight: 109 grams
  • BISAC Subject(s): Pharmacology

Os adjuvantes � base de plantas s�o relativamente �nicos por apresentarem poucas dessas limita��es e t�m a vantagem de serem potentes indutores da imunidade celular e humoral, tornando-os adequados para um amplo espectro de vacinas profil�ticas e terap�uticas. Altos t�tulos de anticorpos e uma resposta relativamente uniforme podem ser frequentemente alcan�ados com o uso de adjuvantes.No entanto, o al�men tem sido utilizado h� muito tempo como adjuvante para vacinas e apresenta falta de efic�cia e dura��o do efeito ou rea��es locais inaceit�veis. No entanto, a sua utiliza��o como adjuvante de vacinas apresenta limita��es no apoio � resposta mediada por c�lulas. Embora tenham sido propostos v�rios adjuvantes diferentes nas �ltimas d�cadas, a grande maioria n�o foi aprovada para uso humano, com limita��es que incluem falta de efic�cia, toxicidade local ou sist�mica inaceit�vel, dificuldade de fabrico, estabilidade deficiente e custo proibitivo.Neste livro, s�o descritos candidatos � base de plantas isolados de plantas medicinais, que podem ser considerados melhores candidatos a adjuvantes de vacinas em compara��o com o al�men, para melhorar a taxa de seroconvers�o, bem como as citocinas e a prote��o induzida ap�s a vacina��o.

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