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Adjuvants de vaccins à base de plantes by Gupta, Amit

Adjuvants de vaccins à base de plantes

by Amit Gupta
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Book cover type: Paperback
  • ISBN13: 9786208991210
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Editions Notre Savoir
  • Publisher Imprint: Editions Notre Savoir
  • Publication Date:
  • Pages: 72
  • Original Price: GBP 31.23
  • Language: French
  • Edition: N/A
  • Item Weight: 109 grams
  • BISAC Subject(s): Pharmacology

Les adjuvants d'origine v�g�tale sont relativement uniques car ils pr�sentent peu de ces limitations et ont l'avantage d'�tre de puissants inducteurs de l'immunit� cellulaire et humorale, ce qui les rend appropri�s pour un large �ventail de vaccins prophylactiques et th�rapeutiques.Des titres d'anticorps �lev�s et une r�ponse relativement uniforme peuvent souvent �tre obtenus par l'utilisation d'adjuvants.Cependant, l'alun est utilis� depuis longtemps comme adjuvant pour les vaccins et pr�sente un manque d'efficacit� et de dur�e d'effet ou des r�actions locales inacceptables. Cependant, son utilisation en tant qu'adjuvant de vaccin pr�sente des limites en ce qui concerne le soutien de la r�ponse � m�diation cellulaire. Bien que plusieurs adjuvants diff�rents aient �t� propos�s au cours des derni�res d�cennies, la grande majorit� d'entre eux n'ont pas r�ussi � �tre approuv�s pour un usage humain, avec des limitations telles que le manque d'efficacit�, une toxicit� locale ou syst�mique inacceptable, la difficult� de fabrication, une faible stabilit� et un co�t prohibitif. Dans ce livre, nous d�crivons un candidat v�g�tal isol� � partir de plantes m�dicinales, qui peut �tre consid�r� comme un meilleur adjuvant de vaccin que l'alun, afin d'am�liorer le taux de s�roconversion ainsi que les cytokines et la protection induite apr�s la vaccination.

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